Controlled trial of methandienone in treatment of diabetic retinopathy.

Hunter, Peter; Cotton, Susan G.; Kelsey, J. H.; Bloom, Arnold

doi:10.1136/bmj.3.5566.651

Cited by 11 publications

(3 citation statements)

References 6 publications

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“…Table 4 expresses the number of eyes in which each exudate change occurred as a percentage of the total number of eyes studied, and also summarizes the findings in other reported studies. 3 -11 " 13 Statistical analysis of the results obtained in the present study shows the difference between the exudate changes observed in the treated patients and those in the control subjects to be highly significant. When the changes are expressed in terms of patient numbers as in ) 3 3 5 3 1 6 1 1 7 1 3 1 2 1 2 5 4 2 2 3 3 1 1 4 3 Diabetic treatment I I I CP I I CP I D CP I CP CP CP CP I I D I CP I CP I D Change in visual acuity was adjudged to be significant if it altered by two or more parameters in either the Snellen or the reading acuity tests, e.g., 6/6 to 6/12 or N 5 to N 8 .…”

Section: Fig 3 No 6 R Eye ( a ) Initial W 3 Exudate; (B) Improvinmentioning

confidence: 64%

“…Table 5 shows considerable differences between the three initial fasting triglyceride values in many individual subjects, some of whom were admitted to hospital for the withdrawal of blood on three consecutive days (Nos. 1,4,6,13,18), and others who had reported as outpatients on successive days or consecutive weeks (Nos. 9,12,14,15,17,22).…”

Section: Fig 3 No 6 R Eye ( a ) Initial W 3 Exudate; (B) Improvinmentioning

confidence: 98%

“…In three other patients Atromid reduced initial hypercholesterolemia; in two (Nos. 13 [R], 14 [L]) exudates improved in one eye only and in the other (No. 22) no improvement occurred.…”

Section: Fig 3 No 6 R Eye ( a ) Initial W 3 Exudate; (B) Improvinmentioning

confidence: 98%

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A Three-Year Trial of Atromid Therapy in Exudative Diabetic Retinopathy

et al. 1968

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A three-year trial of Atromid treatment in exudative diabetic retinopathy was carried out in twenty-three patients and twenty-five controls.In comparison with those of the controls the eyes of the Atromid-treated patients showed a highly significant decrease in hard waxy exudates (p =z <^ 0.0001) which was not, however, accompanied by appreciable improvement in visual acuity. No improvement in the vascular retinal lesions occurred.The initial severity of the exudative lesions was not related to the fasting serum cholesterol or triglyceride levels; there was also no correlation between the effect of Atromid on the exudates and on these serum lipids.The way in which Atromid might influence exudate deposition and its possible use in the treatment of exudative diabetic retinopathy are discussed. DIABETES 77:458-67, July, 1968.

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Section: Fig 3 No 6 R Eye ( a ) Initial W 3 Exudate; (B) Improvinmentioning

confidence: 64%