Controlling the Assembly of C2-Symmetric Molecular Tectons Using a Thiocarbamate Appended Carbocyclic Cleft Molecule Analogous to Tröger’s Base

Abstract

Loughborough University Institutional Repository gontrolling the ssemly of gPEsymmetri moleulr tetons using thiormte ppended royli left moleule nlogous to r¤ oger9s se his item ws sumitted to voughorough niversity9s snstitutionl epository y theGn uthorF Citation: veiD xF FFF et lFD PHITF gontrolling the ssemly of gPE symmetri moleulr tetons using thiormte ppended royli left moleule nlogous to r¤ oger9s seF grystl qrowth nd hesignD IT @UAD ppF QVRT!QVSPF Additional Information:• his doument is the eepted wnusript version of ulished ork tht ppered in finl form in grystl qrowth nd hesignD opyright emerin ghemil oiety fter peer review nd tehnil editing y the pulisherF o ess the finl edited nd pulished work seeX httpXGGpusFsForgGdoiGsGIHFIHPIGsFgdFTHHQVV ABSTRACTBy way of appending the C 2 -symmetric carbocyclic cleft diol with thiocarbamates with varying substituents, significant control of the hydrogen bonded network can be achieved.Smaller alkyl substituents lead to the formation of stacked columns of components with the apex of one molecule suitably aligned in the cleft of a second. Aryl substituents however, lead to the formation of ribbons via an H-bonding network. Additionally, the packing of these ribbons into networks is considerably different between the enantiopure and racemic clefts, with the latter giving rise to channels within the crystal structure.2

Electrochemical Ring-Opening Dicarboxylation of Strained Carbon–Carbon Single Bonds with CO2: Facile Synthesis of Diacids and Derivatization into Polyesters

“…With the optimized reaction conditions identified, we first investigated the scope of 1,2-diarylcyclopropanes (Scheme ). Compared with previous work, which was mainly limited to the synthesis of symmetrical diacids, our method was applicable for both symmetrical and unsymmetrical ones. Moreover, different from electro-oxidative ring-opening difunctionalization reactions, which are limited to donor–acceptor cyclopropanes, our reaction was applicable to a broader substrate scope.…”

A new monoclinic polymorph ofN-(3-methylphenyl)ethoxycarbothioamide: crystal structure and Hirshfeld surface analysis

“…Molecules of the general formula ROC( S)N(H)R 0 [R = alkyl, aryl], O-thiocarbamates, are readily prepared from the reaction of an alcohol, ROH, with an isothiocyanide derivative, R 0 N C S. Since the first report of the structure of EtOC( S)N(H)Ph (Taylor & Tiekink, 1994), these molecules have attracted the interest of the crystal engineering community. This interest arises primarily because of the propensity of these molecules to form thioamide-N-HÁ Á ÁS(thione) hydrogen bonds (Ho et al, 2005;Kuan et al, 2007;Slater et al, 2016) and the ability of these molecules to form co-crystals with pyridyl-like molecules (Ellis et al, 2009). The neutral molecules can complex bis(phosphane)copper(I) chloride to reveal fascinating intramolecular phenyl-C-HÁ Á Á(quasi-chelate ring) interactions where the -system is the hydrogen-bond mediated (CuClÁ Á ÁHNCS) ring (Yeo et al, 2014); intermolecular versions of C-HÁ Á Á(quasi-chelate ring) interactions are also known (Zukerman-Schpector et al, 2016).…”

N-Centered Chiral Self-Sorting and Supramolecular Helix of Tröger's Base-Based Dimeric Macrocycles in Crystalline State

“…Currently, most of chiral self-sorting behaviors occured in the simple molecular system and even in the supramolecular self-assembly (Yashima et al, 2016) were based on carbon stereogenic factor . To the best of our knowledge, few studies have been attempted to elucidate chiral self-sorting properties based on nitrogen stereogenic factor so far, although nitrogen stereogenic factor , particularly nitrogen stereogenic center was one of the important sources of chirality (Slater et al, 2016; Feng et al, 2018). In order to understand broadly and deeply chiral behaviors: chiral recognition, chiral amplification, and chiral transmission, it was significant to fabricate chiral system possessing nitrogen stereogenic factors .…”