This paper reports on a novel concept of thermally stable lattice structures for next-generation refractive optical systems. The aim is to develop a metallic mount for optical lenses based on auxetic structures fabricated by additive manufacturing. Auxetic structures exhibit an effective negative Poisson ratio at the macroscopic level. This property is used to develop a mounting structure that compensates for thermal defocus between refractive optical elements. Numerical and experimental studies of the mechanical behavior of additively manufactured body-centered cubic cells provide the basis for the development of this application-specific mounting structure. Several static load cases are analyzed and deviations between numerical and experimental data are examined to quantify differences in dependence of element type, element size, and manufacturing-related geometrical inaccuracies. These results are used to compare the numerical analysis of the Poisson ratio of an auxetic unit cell with the analytical descriptions. This comparison is then applied to two-dimensional auxetic unit cell compounds. These studies provide the basis for the further development process of an auxetic mounting structure.