2019
DOI: 10.24875/ric.18002626
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Controversies and Limitations in the Diagnosis of Chronic Obstructive Pulmonary Disease

Abstract: Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality worldwide. While the cutoff point to define airflow obstruction has been controversial, it is widely accepted that the spirometry test is vital, as well as performing it after using a bronchodilator. The 6-second spirometry and the forced expiratory volume in 1 second/forced expiratory volume in 6 seconds (FEV 1 /FEV 6) have demonstrated validity for defining obstruction, and it would be advisable to incorporate th… Show more

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Cited by 3 publications
(2 citation statements)
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“…The disease is associated with an abnormal inflammatory response of the lung to harmful particles or gases, especially tobacco, with significant systemic repercussions. 1 , 2 The prevalence of COPD is high worldwide and there is a trend towards a continued increase. 2 , 3 In Spain, the estimated prevalence of COPD is 11.8% (EPISCAN II) in people aged 40 or older.…”
Section: Introductionmentioning
confidence: 99%
“…The disease is associated with an abnormal inflammatory response of the lung to harmful particles or gases, especially tobacco, with significant systemic repercussions. 1 , 2 The prevalence of COPD is high worldwide and there is a trend towards a continued increase. 2 , 3 In Spain, the estimated prevalence of COPD is 11.8% (EPISCAN II) in people aged 40 or older.…”
Section: Introductionmentioning
confidence: 99%
“…Inflammation possesses a key role in the development of chronic obstructive pulmonary disease resulting in structural changes in the lungs 5 . Although it presents a variety in clinical manifestations, there are few cardinal symptoms that describe it and these are dyspnea and chronic and productive cough 6 . Especially, dyspnea is the reason that will lead a person to seek medical help.…”
Section: Introductionmentioning
confidence: 99%