Controversies in Antibiotic Use for Chronic Wet Cough in Children

Liptzin, Deborah R.; Neemann, Kari; McCulloh, Russell; Singleton, Rosalyn; Smith, Paul; Carlson, John C.

doi:10.1016/j.jpeds.2023.113762

Cited by 2 publications

(2 citation statements)

References 40 publications

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“…In our case, the most frequent causes of chronic cough could be ruled out by analyzing the characteristics of the cough. Protracted bacterial bronchitis manifests by a chronic productive cough [9,10], but the presented girl had a dry cough. Diagnosis of asthma could be excluded by the constant absence of wheezing which is believed to be a key feature of asthma [11].…”

Section: Discussionmentioning

confidence: 87%

“…Protracted bacterial bronchitis is diagnosed in 11-41% of children presenting with chronic cough [9]. The gold standard for diagnosis of protracted bacterial bronchitis is flexible bronchoscopy with lavage, but as the method is invasive it is not routinely performed [10]. According to guidelines, supported by Australian clinical trials, it is recommended to establish a diagnosis clinically based on a continuous wet cough of more than four weeks duration, absence of symptoms or signs suggestive of other causes of productive cough, and resolving of symptoms after a two-week course of an appropriate oral antibiotic treatment [9].…”

Section: Discussionmentioning

confidence: 99%

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Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Grinevica,

Udre,

Balodis

et al. 2024

Brain Sciences

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Chronic cough in children and adolescents can be troublesome both to the patient and the whole family. The most common causes of chronic cough in children are protracted bacterial bronchitis and bronchial asthma. However, differential diagnostic workup and treatment can become complicated when a cough of different etiology is encountered, especially in a child having a complex medical history for an unrelated pathology. A cough lacking any identified somatic cause and response to medical treatment in combination with core clinical features of tics that include suppressibility, distractibility, suggestibility, variability, and the presence of a premonitory sensation is labeled tic cough. Here we discuss a case of an adolescent who had atrophy of the corpus callosum and a history of ventriculoperitoneal shunting due to hydrocephalus caused by stenosis of the sylvian aqueduct, but now presented with a debilitating dry cough lasting for several months. After physical causes of cough were ruled out, the diagnosis of tic cough was reached, and multidisciplinary treatment ensured complete recovery. To the best of our knowledge, this is the first reported case showing coincidence of tic cough and hydrocephalus. The co-occurrence of non-syndromic corpus callosum atrophy and tic cough might hypothetically suggest a predisposing pathogenetic link via reduced signaling through cortical inhibitory neurons; further studies are needed. The importance of careful assessment of medical history, clinical picture, and features of the cough itself are emphasized in order to reach the correct diagnosis. Increased awareness of medical society is mandatory to recognize tic cough and to distinguish it from the neurologic manifestations of organic brain pathology.

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Grinevica,

Udre,

Balodis

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

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Pediatric Pulmonology 2023 year in review: Rare and diffuse lung disease

Hinds,

Nevel,

Liptzin

et al. 2024

Pediatric Pulmonology

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The field of pediatric rare and diffuse lung disease continues its maturation as research advances the understanding of diagnosis and treatment of children's interstitial lung disease, noncystic fibrosis bronchiectasis, and primary ciliary dyskinesia. The rarity and breadth of these conditions make them challenging to study, yet we continue to make progress in our understanding of pathophysiology, genotype/phenotype relationships, and treatment. Papers published on these topics in Pediatric Pulmonology and other journals in 2023 describe the power of multicenter cooperation and patient registries, enhance our understanding of pathophysiology and genotype/phenotype relationships, and report progress in treatments. In this review, we hope to increase awareness and knowledge of these conditions and to inspire future research.

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Controversies in Antibiotic Use for Chronic Wet Cough in Children

Cited by 2 publications

References 40 publications

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Pediatric Pulmonology 2023 year in review: Rare and diffuse lung disease

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