Controversies in neuro-ophthalmology: Steroid therapy for traumatic optic neuropathy

Saxena, Rohit; Singh, Digvijay; Menon, Vimla

doi:10.4103/0301-4738.146021

Cited by 18 publications

(8 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9,10 Some studies had shown good visual outcomes with steroids 11,12 and some studies revealed the high rate of spontaneous recovery. 13…”

Section: Discussionmentioning

confidence: 99%

Visual outcome in patients with traumatic optic neuropathy

Babu¹,

Manjula²,

Kumar³

2021

IJCEO

View full text Add to dashboard Cite

To assess the visual outcome in patients with decreased vision due to traumatic optic neuropathy who were managed differently either by conservative method, iv corticosteroids, or decompression surgery Materials and Methods: A retrospective study was conducted involving 25 consecutive patients (25 eyes) with unilateral blindness as a result of head injury with regard to their visual status, CT scan, and MRI scan. Results: Patients were divided into 3 groups. In first group, 12 of 14 eyes treated with intravenous followed by oral corticosteroids had shown 2 line improvement of visual acuity, where as in the second group, 8 of 9 patients treated conservatively had shown 1 line of improvement and in third group of patients who had decompression surgery, 2 of 2 had shown 1 line of improvement. The vision of 3 patients remained the same when they presented 1 month after injury. Conclusion: Patients treated with intravenous followed by oral corticosteroids have better visual outcome compared to those who underwent conservative management and decompression surgery. Patients who had vision better than counting fingers and initiation of treatment with in 8 hours of injury showed significant improvement.

show abstract

“…9,10 Some studies had shown good visual outcomes with steroids 11,12 and some studies revealed the high rate of spontaneous recovery. 13…”

Section: Discussionmentioning

confidence: 99%

Visual outcome in patients with traumatic optic neuropathy

Babu¹,

Manjula²,

Kumar³

2021

IJCEO

View full text Add to dashboard Cite

show abstract

“…Optic nerve injury mechanisms in these patients can be categorized into two types: direct injury and indirect injury [22] . Direct injury often arises from violence directly impacting the outer edge of the orbit, while indirect injury frequently occurs due to optic nerve-related blood vessel spasm resulting from violence to the supraorbital margin and nasal bone [23][24] .…”

Section: Discussionmentioning

confidence: 99%

Effects of light perception on visual function recovery in patients with traumatic optic neuropathy

Wang

Xue

Tan

et al. 2023

Preprint

View full text Add to dashboard Cite

Objective This study aimed to assess the impact of light perception presence or absence on visual function recovery in patients with traumatic optic neuropathy (TON). Methods A retrospective analysis was conducted on the clinical data of 206 TON patients. Based on the presence or absence of light perception after injury, patients were categorized into a light perception group and a non-light perception group. A comparison was made between the two groups regarding visual acuity recovery before and after treatment. Results The non-light perception group comprised 63 patients, with a treatment effectiveness rate of 39.68%. The light perception group consisted of 143 patients, with a treatment effectiveness rate of 74.83%. The difference between the two groups was statistically significant (χ2 = 23.464, P < 0.01). Subgroup analysis indicated that surgical treatment appeared to be more effective than steroid hormone therapy for patients with light perception. Conversely, for patients without light perception, there was no significant difference in the effectiveness of the two methods. Conclusion The total effectiveness rate of the light perception group was significantly higher than that of the non-light perception group, suggesting that patients with light perception before treatment experience better outcomes compared to those without light perception. Treatment choices should be individualized to ensure optimal results.

show abstract

“…Steroid therapy remains the mainstay of treatment. Saxena et al, 10 in their review concluded that methylprednisolone (30 mg/kg loading dose, followed by 5.4 mg/kg/h for 24 h) started within 8 h of injury result in a significant improvement in neurological outcome compared with placebo. Similarly, Sitaula et al, 11 in their retrospective study on traumatic optic neuropathy on 39 patients observed improvement in visual acuity in 5 out of 8 patients who presented within 48 hours of injury and concluded that earlier the treatment was started following injury, better was the prognosis.…”

Section: Discussionmentioning

confidence: 99%

Reversal of optic nerve function and visual outcome in traumatic optic neuropathy

Singh¹,

Kubrey²,

Kumar³

2021

IJCEO

View full text Add to dashboard Cite

Traumatic optic neuropathy (TON) refers to an acute injury to the optic nerve secondary to ocular trauma. The study was conducted to evaluate the visual outcome in cases of TON and to study reversal of optic nerve function after emergency ophthalmic intervention. Objectives: To evaluate the visual outcome in cases of TON, study the factors affecting final visual outcome and to evaluate the optic nerve function in cases of TON. Methodology: The present study was a Prospective observational study, 49 patients presented after ocular trauma in the

show abstract

Controversies in neuro-ophthalmology: Steroid therapy for traumatic optic neuropathy

Cited by 18 publications

References 13 publications

Visual outcome in patients with traumatic optic neuropathy

Visual outcome in patients with traumatic optic neuropathy

Effects of light perception on visual function recovery in patients with traumatic optic neuropathy

Reversal of optic nerve function and visual outcome in traumatic optic neuropathy

Contact Info

Product

Resources

About