Hybrid nanofluids (HNF’s) can perform as promising heat transfer fluids because of their enhanced thermo-physical characteristics. However, there are certain limitations of using them at higher concentrations. Moreover, lot of works on hybrid nanofluids focussed greatly on assessing thermal conductivity and viscosity. But the other parameters like specific heat and density also play an important role in heat transfer applications in addition to the volume concentration. Also, the effect of the combination of different nano particles on heat transfer is also a crucial area. Hence in this work, it is aimed to determine the thermo-physical characteristics of MWCNT/ZnO hybrid nanofluids (70:30) at varied loading and temperatures. Two step strategy was employed to prepare the (HNF’s) at distinct loadings varying in the range of 0.01%–0.05% and at a range of temperatures of 30°C–70°C with base fluid as water. The mixture’s ratios were 30:70 of MWCNT and ZnO, respectively. HNF’s exhibited an improved thermal conductivity in comparison to the original fluid, which was 80% more than the base fluid. With the rise in the temperature, the density, viscosity and specific heat all trended downward. There is an increase in the density and viscosity with the increase in the volume concentration of the hybrid nano particles. This work suggested that the MWCNT and ZnO hybrid nanofluids are better heat transfer fluids for enhancing the heat transfer and can emerge as efficient coolants for the applications of heat transfer.