<p><span lang="EN-US">Glioblastoma multiforme (GBM) is a high-grade brain tumor that is extremely dangerous and aggressive. Due to its rapid development rate, high-grade cancers require early detection and treatment, and early detection may possibly increase the chances of survival. The current practice of GBM detection is performed by a radiologist; due to the enormous number of cases, it is nevertheless tedious, intrusive, and error-prone. Thus, this study attempted a substantial adaptive artificial bee colony (a-ABC) algorithm implementation in providing a non-invasive approach for GBM detection. The basic statistical intensity-based analysis of minimum (minGL), maximum (maxGL), and mean (meanGL) of grey level data was employed to investigate the GBM's feature properties. The a-ABC's performance for adaptive GBM detection identification was evaluated using T1-weighted (T1), T2-weighted (T2), fluid attenuated inversion recovery (FLAIR), and T1-contrast (T1C) which are four different magnetic resonance imaging (MRI) imaging sequences. Hundred and twenty MRI of GBM images were assessed in total, with 30 images per imaging sequence. The overall mean of GBM detection accuracy percentage was 93.67%, implying that the proposed a-ABC algorithm is capable of detecting GBM brain tumors. Other feature extraction strategies, on the other hand, may be added in the future to enhancee the performance of feature extraction. </span></p>