Conventional and microwave-assisted synthesis of hyperbranched and highly branched polylysine towards amphiphilic core–shell nanocontainers for metal nanoparticles

Ho, Chau Hon; Thiel, Matthias; Celik, Seref; Odermatt, Erich K.; Berndt, Ingo; Thomann, Ralf; Tiller, Joerg C.

doi:10.1016/j.polymer.2012.08.032

Cited by 12 publications

(9 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this synthesis, the stabilizing agent can have a dual function, i.e., also acting as a reducing agent in the same reaction [61]. Appropriate average size, polydispersity, and shape of AgNPs can be achieved by controlling the nucleation stage, i.e., by monitoring the experimental parameters, such as the precursor used in the reaction, reducing agents, reagent concentration, pH, and temperature [62][63][64][65].…”

Section: Conventional Chemistrymentioning

confidence: 99%

“…In addition, it has also been proven that the use of polymeric compounds, such as polyvinylpyrrolidone (PVP), polyacrylates, polyvinyl alcohol (PVA), polyacrylonitrile, polyacrylamide, or polyethylene glycol (PEG), is also useful. Finally, stabilization Appropriate average size, polydispersity, and shape of AgNPs can be achieved by controlling the nucleation stage, i.e., by monitoring the experimental parameters, such as the precursor used in the reaction, reducing agents, reagent concentration, pH, and temperature [62][63][64][65].…”

Section: Conventional Chemistrymentioning

confidence: 99%

“…They were able to obtain hybrid AgNPs inside a polylysine shell modified by different fatty acids. This green synthesis method was able to develop AgNPs of mean size between 2 and 5 nm [65].…”

Section: Green Chemistrymentioning

confidence: 99%

See 2 more Smart Citations

Metal-Based Nanoparticles as Antimicrobial Agents: An Overview

et al. 2020

View full text Add to dashboard Cite

Metal-based nanoparticles have been extensively investigated for a set of biomedical applications. According to the World Health Organization, in addition to their reduced size and selectivity for bacteria, metal-based nanoparticles have also proved to be effective against pathogens listed as a priority. Metal-based nanoparticles are known to have non-specific bacterial toxicity mechanisms (they do not bind to a specific receptor in the bacterial cell) which not only makes the development of resistance by bacteria difficult, but also broadens the spectrum of antibacterial activity. As a result, a large majority of metal-based nanoparticles efficacy studies performed so far have shown promising results in both Gram-positive and Gram-negative bacteria. The aim of this review has been a comprehensive discussion of the state of the art on the use of the most relevant types of metal nanoparticles employed as antimicrobial agents. A special emphasis to silver nanoparticles is given, while others (e.g., gold, zinc oxide, copper, and copper oxide nanoparticles) commonly used in antibiotherapy are also reviewed. The novelty of this review relies on the comparative discussion of the different types of metal nanoparticles, their production methods, physicochemical characterization, and pharmacokinetics together with the toxicological risk encountered with the use of different types of nanoparticles as antimicrobial agents. Their added-value in the development of alternative, more effective antibiotics against multi-resistant Gram-negative bacteria has been highlighted.

show abstract

Section: Conventional Chemistrymentioning

confidence: 99%

Section: Conventional Chemistrymentioning

confidence: 99%

See 1 more Smart Citation

Metal-Based Nanoparticles as Antimicrobial Agents: An Overview

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Among the numerous available HPs, amine-or sulfur-containing HPs are widely used due to their stronger interaction with metal NCs. [320][321][322][323][324][325] Based on the specific properties of the metallic elements themselves, the corresponding metal NCs have been widely used as catalysts, [320][321][322][323] disinfectants, 324 sensors, 325,326 and so on. Without the undesired aggregation, they exhibited high catalytic activity and good reusability.…”

Section: Hp-stabilized Nanocrystalsmentioning

confidence: 99%

Hyperbranched polymers: advances from synthesis to applications

et al. 2015

View full text Add to dashboard Cite

Hyperbranched polymers (HPs) are highly branched three-dimensional (3D) macromolecules. Their globular and dendritic architectures endow them with unique structures and properties such as abundant functional groups, intramolecular cavities, low viscosity, and high solubility. HPs can be facilely synthesized via a one-pot polymerization of traditional small molecular monomers or emerging macromonomers. The great development in synthetic strategies, from click polymerization (i.e., copper-catalyzed azide-alkyne cycloaddition, metal-free azide-alkyne cycloaddition, strain-promoted azide-alkyne cycloaddition, thiol-ene/yne addition, Diels-Alder cycloaddition, Menschutkin reaction, and aza-Michael addition) to recently reported multicomponent reactions, gives rise to diverse HPs with desirable functional/hetero-functional groups and topologies such as segmented or sequential ones. Benefiting from tailorable structures and correspondingly special properties, the achieved HPs have been widely applied in various fields such as light-emitting materials, nanoscience and technology, supramolecular chemistry, biomaterials, hybrid materials and composites, coatings, adhesives, and modifiers. In this review, we mainly focus on the progress in the structural control, synthesis, functionalization, and potential applications of both conventional and segmented HPs reported over the last decade.

show abstract

“…10 The combination effects of Ply and nisin was also used to evaluate the synergistic action of these compounds against Bacillus subtilis (B. subtilis), which indicated that the uptake of Ply into cells was promoted through nisin, subsequently Ply interacted with the intracellular DNA achieving a synergistic effect. 13 ATRP is a controllable polymerization method with organic bromide as initiator and transition metal complexes as carrier of bromine atom, and its controlling of polymerization reaction depends on the dynamic equilibrium of active species and dormant species. 12 Hyperbranched amphiphilic polymeric systems can be used as versatile nanocontainers and templates with great potential in medicine application elds.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of amphiphilic fluorescent polylysine nanoparticles by atom transfer radical polymerization (ATRP) and their application in cell imaging

et al. 2015

View full text Add to dashboard Cite

Due to the good biocompatibility, 3-polylysine (Ply) has been extensively investigated for various biomedical applications. In this study, a fluorescent monomer (named Flu-MA) was firstly synthesized through acylation reaction of fluorescein by methacryloyl chloride, and the initiator of 3-polylysine bromide (named Ply-Br) was prepared by the introduction of a bromine atom into Ply by the acylation reaction of Ply with abromoisobutyryl bromide. Subsequently, a novel amphiphilic fluorescent polymer (Flu-Ply) was successfully fabricated by ATRP via incorporation of Flu-MA monomer into Ply chains for the first time.The structure and properties of the obtained Flu-Ply fluorescent polymer were investigated in detail by 1 H NMR, TEM, UV-vis, FL and FTIR, and the results confirmed the successful incorporation of Flu-MA into Ply by ATRP. As a result of Flu-MA and Ply respectively endowing the as-prepared Flu-Ply polymer with fluorescence and water dispersibility, it tended to self-assemble into fluorescent organic nanoparticles (FONs) with excellent biocompatibility. More importantly, the good fluorescence, uniform spherical morphology, excellent biocompatibility and water dispersibility of Flu-Ply FONs exhibited an attractive prospect for bioimaging applications.

show abstract

Conventional and microwave-assisted synthesis of hyperbranched and highly branched polylysine towards amphiphilic core–shell nanocontainers for metal nanoparticles

Cited by 12 publications

References 42 publications

Metal-Based Nanoparticles as Antimicrobial Agents: An Overview

Metal-Based Nanoparticles as Antimicrobial Agents: An Overview

Hyperbranched polymers: advances from synthesis to applications

Fabrication of amphiphilic fluorescent polylysine nanoparticles by atom transfer radical polymerization (ATRP) and their application in cell imaging

Contact Info

Product

Resources

About