2019
DOI: 10.1177/1747519819831848
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Conventional and microwave-irradiated synthesis of new bischalcone derivatives

Abstract: A series of 12 novel methyl- and halogen-substituted bischalcones containing an azo linkage was synthesized by a Claisen–Schmidt condensation between ( E)-1-{4-[(4-acetyl-2-hydroxyphenyl)diazenyl]phenyl}ethanone and various araldehydes using microwave irradiation and conventional procedures and the results were compared.

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Cited by 2 publications
(2 citation statements)
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“…[1] Due to their potent biological activities, various chalcones bearing azo, sulfonamide, halogen and hydroxy groups have been synthesized . [2][3][4] Especially, sulfonamide chalcones are prominent with their carbonic anhydrase and anti-cancer activities. [4,5] Carbonic anhydrase enzymes (CAs, EC 4.2.1.1) are a family of enzymes with physiological hydratase activity.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…[1] Due to their potent biological activities, various chalcones bearing azo, sulfonamide, halogen and hydroxy groups have been synthesized . [2][3][4] Especially, sulfonamide chalcones are prominent with their carbonic anhydrase and anti-cancer activities. [4,5] Carbonic anhydrase enzymes (CAs, EC 4.2.1.1) are a family of enzymes with physiological hydratase activity.…”
Section: Introductionmentioning
confidence: 99%
“…Chalcone and its derivatives, both natural and synthetically significant, have a major role in chemical structures associated with various pharmacological activities [1] . Due to their potent biological activities, various chalcones bearing azo, sulfonamide, halogen and hydroxy groups have been synthesized [2–4] . Especially, sulfonamide chalcones are prominent with their carbonic anhydrase and anti‐cancer activities [4,5] …”
Section: Introductionmentioning
confidence: 99%