Conventional versus daylight photodynamic therapy in the treatment of erosive pustular dermatosis of the scalp

Arteaga-Henriquez, Maria; González-Hernández, Sorahaya; García-Peris, E.

doi:10.1111/dth.13220

Cited by 1 publication

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Kroumpouzos and colleagues recommend avoiding MAL-PDT because MAL is more lipophilic than ALA and, therefore, penetrates deeper into the skin and may cause excessive trauma [7]. In addition, the incubation period in MAL-PDT was 3 h [27,98] whereas, in the above ALA-PDT series was 1 h [7,8,63]-the more prolonged incubation of the MAL photosensitizer may also cause excessive tissue trauma that increases the risk of triggering PDT. A more prolonged incubation (2 h) of ALA may also explain why ALA-PDT triggered EPD in the case reported by Madray et al [29].…”

Section: Photodynamic Therapymentioning

confidence: 99%

See 1 more Smart Citation

Erosive Pustular Dermatosis: Delving into Etiopathogenesis and Management

Bhargava

Yumeen

Henebeng

et al. 2022

Life

View full text Add to dashboard Cite

Erosive pustular dermatosis (EPD) is a chronic inflammatory skin disorder that usually affects mature individuals. It predominantly affects the scalp and can lead to scarring alopecia. Risk factors include actinic damage and androgenetic alopecia. A traumatic insult to the skin is considered a vital trigger of the condition. EPD is a diagnosis of exclusion; thus, several neoplastic, infectious, vesiculobullous, and inflammatory conditions should be ruled out. Biopsy and clinicopathologic correlation are required to differentiate between EPD and these entities. A dysregulated, chronic immune response is considered central to the etiopathogenesis of EPD. We performed an evidence-based systematic review of the management options. There were predominantly studies with level IV and V evidence and only two with level III. Despite the responsiveness of EPD to potent topical steroids, such as clobetasol propionate, recurrence occurs after treatment withdrawal. With the available data, tacrolimus 0.1%, curettage-assisted aminolevulinic acid-photodynamic therapy, and systemic retinoids can be considered second-line options for EPD with a role in maintenance regimens. However, controlled data and more powerful studies are needed to make solid recommendations.

show abstract

Section: Photodynamic Therapymentioning

confidence: 99%

“…Another study showed that daylight PDT and conventional PDT have similar efficacy, which can be used in resource-limited settings for the best results in a single treatment [98]. PDT has been safely combined with fractional thulium 1927 nm laser with a complete response of EPD [99].…”

Section: Photodynamic Therapymentioning

confidence: 99%