Agritourism is a complex activity, a chance maybe today to ensure both human health and the “health” of the environment and rural settlements in order to achieve a most wanted desideratum, the sustainability of the rural environment. The idea of this paper starts from the trend of the current period, meaning the strong emphasis on natural, organic, bio, in all human activities, health and environment, in a word, sustainability. The necessity of implementing the sustainability of activities, health and environment in rural areas, taking into account the agritourism field, was a subject pursued in the study, taking as area of study the mountainous rural environment, the reason of this choice deriving from the fact that the mountain area offers great opportunities for agritourism development, the practice of which is even necessary in the current period. The sustainability of agritourism on rural health and environment cannot be dissociated from the economic, social and cultural life of the community in which it manifests itself, and has a multiplier effect on all the domains with which it interacts. So the purpose of the paper is to follow the development of the agritourism field and, based on some present information, to make a future forecast for some specific indicators, to highlight the representative aspects related to the development and capitalization of guesthouses from a rural mountain environment through agritourism and to come up with a forecast for future transformations that need to take place in the studied area in order to support the sustainable development of the human environment through agritourism.