Convergent paired electrochemical synthesis of symmetric dispiro and spiropyrimidine derivatives based on reduction of para-nitrophenol

Khoram, Mahmood Masoudi; Mohamadighader, Niloofar; Nematollahi, Davood; Khazalpour, Sadegh; Masoumi, Hossein; Alizadeh, Hojjat

doi:10.1016/j.jelechem.2021.115946

Cited by 2 publications

(1 citation statement)

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“…Using a new type of green electrochemical method, Khoram et al synthesized pyrimidine derivatives containing spiro and dispiro rings (Figure 33c ). [ 333 ] P –nitrophenol is electrochemically converted into reactive intermediates, and the reactions with barbituric acids are essential for the production of target products. Qiao et al.…”

Section: Paired Electrolysis Of Organic Moleculesmentioning

confidence: 99%

Electro‐Synthesis of Organic Compounds with Heterogeneous Catalysis

et al. 2022

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Electro-organic synthesis has attracted a lot of attention in pharmaceutical science, medicinal chemistry, and future industrial applications in energy storage and conversion. To date, there has not been a detailed review on electro-organic synthesis with the strategy of heterogeneous catalysis. In this review, the most recent advances in synthesizing value-added chemicals by heterogeneous catalysis are summarized. An overview of electrocatalytic oxidation and reduction processes as well as paired electrocatalysis is provided, and the anodic oxidation of alcohols (monohydric and polyhydric), aldehydes, and amines are discussed. This review also provides in-depth insight into the cathodic reduction of carboxylates, carbon dioxide, C=C, C≡C, and reductive coupling reactions. Moreover, the electrocatalytic paired electro-synthesis methods, including parallel paired, sequential divergent paired, and convergent paired electrolysis, are summarized. Additionally, the strategies developed to achieve high electrosynthesis efficiency and the associated challenges are also addressed. It is believed that electro-organic synthesis is a promising direction of organic electrochemistry, offering numerous opportunities to develop new organic reaction methods.

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Section: Paired Electrolysis Of Organic Moleculesmentioning

confidence: 99%