Conversion improvement for catalytic synthesis of propylene glycol methyl ether acetate by reactive chromatography: Experiments and parameter estimation

Oh, Jae Min; Agrawal, Gaurav; Sreedhar, Balamurali; Donaldson, Megan E.; Schultz, Alfred K.; Frank, Timothy C.; Bommarius, Andreas S.; Kawajiri, Yoshiaki

doi:10.1016/j.cej.2014.08.008

Cited by 19 publications

(18 citation statements)

References 29 publications

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“…Moreover, the final conversion still remained at 46% even after further increasing the catalyst loading. The result was consistent with the results of Oh et al . using Amberlyst‐15.…”

Section: Resultsmentioning

confidence: 99%

“…The esterification reaction of MPA from MP and HAC was reversible, which was generally regarded as a second‐order reaction . The kinetic model for the esterification reaction of MPA could be expressed by the following equation:

d C_{normalMPA} / d t = k_{1} C_{normalMP} C_{normalHAC} - k_{- 1} C_{normalMPA} C_{H 2 O}

Here C MPA , C MP , C HAC and C H2O represent the molarities of MPA, MP, HAC and H 2 O respectively and k 1 and k −1 are the rate constants of the forward and reverse reactions respectively:

k_{1} = A_{1} \exp (- E_{a1} / RT)

k_{- 1} = A_{2} \exp (- E_{a2} / RT)

where A 1 and A 2 are the pre‐exponential factors and E a1 and E a2 are the apparent activation energies of the forward and reverse reactions respectively.…”

Section: Resultsmentioning

confidence: 99%

“…In order to obtain accurate results, MP and resin were first placed in the reactor; after the mixture in the reactor reached the preset reaction temperature, preheated HAC was added. It was found that there was a clear relationship between the temperature and reaction rate in the experiment, which was also confirmed by Oh et al . To avoid aggregation of tiny resin particles, the sampling procedure was finished at low‐speed stirring.…”

Section: Methodsmentioning

confidence: 99%

“…Cation exchange resin catalysts as alternatives have received increasing attention owing to their environment‐friendly benefits and tremendous cost savings . Oh et al . studied the application of reactive chromatography for MPA production with Amberlyst‐15 resin as catalytic adsorbent.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore the MPA reaction was equilibrium‐limited. In a batch reactor, owing to the limitation of chemical equilibrium, the maximum conversion rate of MP achieved was only 46% . In order to increase the reaction conversion rate, the reactive distillation method was used to break the equilibrium by separating the products from the reaction sites .…”

Section: Introductionmentioning

confidence: 99%

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A combination of low‐temperature reactive and extractive distillation for methoxy‐2‐propyl acetate synthesis and separation process: simulations and experiments

Wang

Cai

et al. 2019

J of Chemical Tech & Biotech

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BACKGROUND Esterification of methoxy propanol (MP) and acetic acid (HAC) to methoxy‐2‐propyl acetate (MPA) is a typical reversible reaction. The yield of MPA is low owing to the limitation of chemical equilibrium. In the present study, with the goal of increasing the reaction conversion and preventing the NKC‐9 cation exchange resin catalyst from deactivation at high temperature, a process combining low‐temperature reactive and extractive distillation with cyclohexane (C6H12) as entrainer was investigated by process simulations and experiment methods. RESULTS The intrinsic kinetic parameters were obtained by catalyst activity evaluation in a batch reactor. Binary interaction parameters of thermodynamic models were determined by the measurement and fitting of vapor–liquid equilibrium data. The effects of different operating parameters on the reaction conversion and column performance were examined in detail, and a production process of MPA with an annual output of 56 000 tons was suggested. The results showed that the purity of MPA reached nearly 100% after further purification following reactive distillation, and the reaction temperature was controlled in the range 75–80 °C, which allowed long‐term operation thermal stability of the catalyst. CONCLUSION The developed low‐temperature reactive distillation method ensured a long life of the ion exchange resin catalyst, which should provide insights into further advances of MPA industrial production. © 2019 Society of Chemical Industry

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“…Moreover, the final conversion still remained at 46% even after further increasing the catalyst loading. The result was consistent with the results of Oh et al . using Amberlyst‐15.…”

Section: Resultsmentioning

confidence: 99%

d C_{normalMPA} / d t = k_{1} C_{normalMP} C_{normalHAC} - k_{- 1} C_{normalMPA} C_{H 2 O}

Here C MPA , C MP , C HAC and C H2O represent the molarities of MPA, MP, HAC and H 2 O respectively and k 1 and k −1 are the rate constants of the forward and reverse reactions respectively:

k_{1} = A_{1} \exp (- E_{a1} / RT)

k_{- 1} = A_{2} \exp (- E_{a2} / RT)

where A 1 and A 2 are the pre‐exponential factors and E a1 and E a2 are the apparent activation energies of the forward and reverse reactions respectively.…”