Convulsiones neonatales: diagnóstico y manejo

A, Ledia Troncoso; G, Pedro Menéndez; Hernández, M.

doi:10.4067/s0370-41062001000300002

Cited by 1 publication

(2 citation statements)

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“…Urine culture and blood culture are also performed. (7) The need for other metabolic tests (e.g., arterial pH, blood gases, serum bilirubin, amino acids, and organic acids in urine) or investigation of common drugs of abuse (transferred to the newborn via transplacental or breast milk) depends on the clinical picture. Genetic evaluation should be considered in children with recurrent or refractory seizures of undetermined cause.…”

Section: Laboratory Testsmentioning

confidence: 99%

“…Genetic evaluation should be considered in children with recurrent or refractory seizures of undetermined cause. (7) Brain Imaging Studies Imaging studies are usually performed unless the cause is immediately obvious (e.g., glucose or electrolyte disturbance). MRI is preferred but may not be readily available; in such cases, a brain CT scan is performed.…”

Section: Laboratory Testsmentioning

confidence: 99%

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The utility of lidocaine in neonatal conviction syndrome:a systematic review

Milange,

Estrin

2024

Interamerican Journal of Health Sciences

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BACKGROUND: Lidocaine is a drug belonging to the local anesthetics; it is rapidly distributed in the body and metabolized in the liver. At commonly recommended doses, the therapeutic index of lidocaine remains very high and plasma concentrations remain largely below neurotoxic, cardiotoxic and other thresholds. It is used during various medical procedures, and in the nervous system it acts by binding to a specific site which is the sodium channel receptor of the neural membrane and blocking the passage of ions. The present study is of interest to know the potential usefulness of lidocaine in neonates with convulsive syndrome. In order to implement improvements in the treatment of those who need it. In this way, pediatric neurologists can achieve better results in the interventions to treat this pathology. Methods: In the present systematic review we try to answer and perform a literature search through pubmed and others to analyze the usefulness of lidocaine in neonatal convulsive syndrome and its potential benefit. Results: After the application of the inclusion and exclusion criteria, we will be able to identify the groups of newborns most at risk and the efficacy of lidocaine treatment. Conclusion: It is concluded that lidocaine is the third drug used in neonatal convulsive syndrome for maintenance where it is received as a continuous infusion and is effective in suppressing electroclinical seizures; excessive doses should be avoided as it can also produce convulsions and other adverse effects in children.

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Section: Laboratory Testsmentioning

confidence: 99%

Section: Laboratory Testsmentioning

confidence: 99%