Background: Disability and sexuality are topical issues although they are not given much-deserved attention in most societies, and Zimbabwe is not an exception. The socio-cultural stigma associated with disability adversely impacts sexuality and seeps into the social existence of youth with disability. Youths with disability are assumed to be hypersexual or asexual.Objectives: This article explores the sexuality views and experiences of youth with disability in the context of the negative stigma associated with disability and sexuality in Gweru, Zimbabwe.Method: Semi-structured interviews and focus group discussions were conducted among 20 Gweru youth (18–35 years old) with physical disabilities and five key informants. Perceptions of youth with disability and socio-cultural assumptions regarding their sexuality were analysed.Results: The study established that most youths with disability faced social closure in terms of sexuality, with sparse offerings of sexuality education in their families. One sexual education theme that emerged from this study is sexual abstinence. Some suggestions of more open forms of communication on sexuality and disability also emerged although as a minority view.Conclusion: It was concluded from the study that, most youth feel that they are denied information on sexuality in their families and communities, as they are wrongfully assumed to have no need for it. However, youths with disability do not passively accept the negative perceptions about their sexuality, and they demonstrate their agency in resisting such negative perceptions.Contribution: The study contributes to knowledge on sexuality and disability among youths with disability in contexts where strong traditional beliefs, myths, and misconceptions exist.