Coordination behaviour and biopotency of metal NN salen complexes

El‐Gamel, Nadia E. A.

doi:10.1039/c2ra20733h

Cited by 20 publications

(10 citation statements)

References 46 publications

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“…in biological, medical, and environmental sciences [1]. The Schiff base ligands are quite popular because they are easily prepared by the condensation between carbonyl compounds and amines and also have some biochemical and analytical importance [2]. Hydroxy acetophenone can be used as primary compound for the synthesis of chalcones [3], flavones [4] etc.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization, X-ray crystallography and DNA binding activities of Co(III) and Cu(II) complexes with a pyrimidine-based Schiff base ligand

Pradhan

Banik

Cordes

et al. 2016

Inorganica Chimica Acta

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Characterization, X-ray crystallography and DNA binding activities of Co(III) and Cu(II) complexes with a pyrimidine-based Schiff base ligand, Inorganica Chimica Acta (2015), doi: http://dx.doi.org/10.1016/j.ica. 2015.11.015 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Synthesis

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Section: Introductionmentioning

confidence: 99%

Synthesis, characterization, X-ray crystallography and DNA binding activities of Co(III) and Cu(II) complexes with a pyrimidine-based Schiff base ligand

Pradhan

Banik

Cordes

et al. 2016

Inorganica Chimica Acta

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“…The electronic spectrum of Cd(II) H2BMPDE consists of three bands in the region of 42553, 32258 and 24691 cm -1 . The band at 24691 cm -1 suggested a distorted tetrahedral structure ( Figure 2) (26)(27). The other band at 42553 and 32258 cm -1 was due to charge transfer transition (26)(27)(28).…”

Section: Resultsmentioning

confidence: 99%

Spectral, Thermal and In Vitro Antibacterial Studies on Cadmium(II)– bis(2,2/-methylidenephenol)diaminoethane

Nworie¹

2018

Journal of the Turkish Chemical Society Section A: Chemistry

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The objective of this work is to prepare a new synthetic protocol of the cadmium(II) complex of bis(2,2'-methylylidenephenol)diaminoethane (H2BMPDE) and study the antimicrobial bioefficacy. In this work, we report the extractive method for the synthesis of cadmium(II) complex of bis(2,2'methylidenephenol)diaminoethane from salicylaldehyde, ethylenediamine, hydrochloric acid, and cadmium sulfate in a single, simple step. The ligand and the complex were characterized by FTIR, UV-Vis, 1 H and 13 C NMR, magnetic moment, GC-MS, thermal and elemental analysis. The chemical data indicated the formation of 1:1 (metal:ligand) mole ratio and distorted tetrahedral geometry was suggested as based on spectral data and magnetic moment. The results of preliminary antibacterial study revealed that Cd(II) H2BMPDE complexes prepared from different acids (HCl, HNO3, H2SO4) were effective against clinically important Gram-negative bacteria (Escherichia coli, pseudomonas, Klebsiella) and Gram-positive bacterium (Staphylococcus aureus).The result indicated a new synthetic protocol for the synthesis of H2BMPDE complexes. On the application, H2BMPDE and its complexes could be considered as a potential antibacterial agent with further investigative analysis.

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“…The Schiff base ligands are considered as “privileged ligands” because they are easily prepared by the condensation between aldehydes and imines, and their use of analytical and biological processes on different models has solved many serious problems [2, 3]. Over the past decade, the synthesis of the privileged classes of heterocyclic molecules has become one of the main areas of interest in synthetic chemistry [1, 2].…”

Section: Introductionmentioning

confidence: 99%

“…Bioinorganic chemistry is an emerging interdisciplinary field of science that utilizes Schiff bases and their transition metal complexes for various applications in biological, medical, and environmental sciences [ 1 ]. The Schiff base ligands are considered as “privileged ligands” because they are easily prepared by the condensation between aldehydes and imines, and their use of analytical and biological processes on different models has solved many serious problems [ 2 , 3 ]. Over the past decade, the synthesis of the privileged classes of heterocyclic molecules has become one of the main areas of interest in synthetic chemistry [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

(E)3-2-(1-(2,4-Dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff Base and Its Metal Complexes: A New Drug of Choice against Methicillin-ResistantStaphylococcus aureus

Siddappa

Mane

Manikprabhu

2014

Bioinorganic Chemistry and Applications

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The 3-(2-aminophenyl) quinazolin-2-methyl-4(3H)-one and 2,4-dihydroxyacetophenone undergo condensation to afford (E)3-2-(1-(2,4-dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff base (DHPEAPMQ). The newly synthesized Schiff base (DHPEAPMQ) and its metal complexes were evaluated for their antimicrobial activity against methicillin-resistant Staphylococcus aureus isolated from the Gulbarga region in India. The Cu(II), Ni(II), and Zn(II) complexes of Schiff base (DHPEAPMQ) showed good antimicrobial activity. So, this could be a new drug of choice.

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Coordination behaviour and biopotency of metal NN salen complexes

Cited by 20 publications

References 46 publications

Synthesis, characterization, X-ray crystallography and DNA binding activities of Co(III) and Cu(II) complexes with a pyrimidine-based Schiff base ligand

Synthesis, characterization, X-ray crystallography and DNA binding activities of Co(III) and Cu(II) complexes with a pyrimidine-based Schiff base ligand

Spectral, Thermal and In Vitro Antibacterial Studies on Cadmium(II)– bis(2,2/-methylidenephenol)diaminoethane

(E)3-2-(1-(2,4-Dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff Base and Its Metal Complexes: A New Drug of Choice against Methicillin-ResistantStaphylococcus aureus

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