Coordination modes of bidentate lornoxicam drug with some transition metal ions. Synthesis, characterization and in vitro antimicrobial and antibreastic cancer activity studies

Synthesis, spectroscopic characterization, thermal stability and biological studies of mixed ligand complexes of gemifloxacin drug and 2,2′-bipyridine with some transition metals

“…This confirms the binding of pyridyl nitrogen to the metal ions [29][30][31]. Proposed structures for the complexes are shown in Scheme 2.…”

Synthesis, structural characterization, in vitro antimicrobial and anticancer activity studies of ternary metal complexes containing glycine amino acid and the anti-inflammatory drug lornoxicam

“…The IR spectra of all complexes showed the m(C@N) stretching vibration peak at 1590-1607 cm À1 . This confirms the binding of pyridyl nitrogen to the metal ions [9][10][11][12][13][14][15][16]. The participation of the pyridyl nitrogen is difficult to be discussed as its band overlapped with those of the carboxylate group of the Gly amino acid or the amide(II) stretching vibration band.…”

“…The strong band observed at 1640 cm À1 in the free LOR ligand is assigned to the m(NHCO) stretching vibration [9][10][11][12]. This band is found in the spectra of the complexes at 1630-1659 cm À1 (Table 2) or disappeared in nickel complex indicating the participation of carbonyl oxygen atom in coordination (MAO) [9][10][11][12][13][14][15][16].…”

Synthesis and characterization of cobalt(II), nickel(II) and copper(II)-based potential photosensitizers: Evaluation of their DNA binding profile, cleavage and photocytotoxicity

“…In comparison with the spectra of the Schiff base, all the metal complexes exhibit downward shift of about 11-20 cm -1 in the band of ν(C=N) indicating the participation of azomethine nitrogen in the coordination to metal ion[58].The most notable change in the Schiff base spectral features when coordinated to metal ion is the lower shift of amide ν(C=O) vibration to the extent of about 16-25 cm -1 , suggesting that, the metal is coordinated to the amide carbonyl oxygen atom[59][60][61][62]. As the thiophene is a very poor ligand[63], the ν(C-S) observed at 786 cm -1 in the ligand L remains at the same position in the complexes indicating non-coordination of thiophene ring sulfur to the metal, in agreement with previous results[45,62,[64][65][66]. New bands at 468-475 cm -…”