Abstract.[Purpose] The purpose of this study was to investigate the effects of a resistance and stabilization complex exercise on the strength and cross-sectional area of lumbar muscles of typical adults in their twenties. [Subjects and Methods] For this study, 14 male adults in their twenties were chosen and randomly assigned to either the resistance exercise group (REG, n=7) or the resistance and stabilization exercise group (RSEG, n=7). They then exercised for 50 minutes three times a week for 8 weeks.[Methods] Pegasus was used to measure the strength of the lumbar muscles of the normal adults and computed tomography (CT) images were taken and compared to examine the changing crosssectional areas of the lumbar muscles.[Results] Both groups showed a significant increase in the strength of their lumbar muscles. For the cross-sectional area of the lumbar muscles, only the superficial stabilizer muscle of the REG group showed a significant increase, whereas both the superficial stabilizer and the deep stabilizer muscles of the RSEG group showed a significant increase.[Conclusion] The resistance and stabilization complex exercise for the lumbar muscles had positive effects on both the strength of the lumbar muscles as well as on the cross-sectional areas of the superficial stabilizer and deep stabilizer muscles. Therefore, resistance and stabilization complex exercise appears to be an effective exercise program for the prevention of lower back pain.