Coordinatively Unsaturated Lanthanide(III) Helicates: Luminescence Sensors for Adenosine Monophosphate in Aqueous Media

Abstract

Coordinatively unsaturated double-stranded helicates [(H2 L)2 Eu2 (NO3 )2 (H2 O)4 ](NO3 )4 , [(H2 L)2 Tb2 (H2 O)6 ](NO3 )6 , and [(H2 L)2 Tb2 (H2 O)6 ]Cl6 (H2 L=butanedioicacid-1,4-bis[2-(2-pyridinylmethylene)hydrazide]) are easily obtained by self-assembly from the ligand and the corresponding lanthanide(III) salts. The complexes are characterized by X-ray crystallography showing the helical arrangement of the ligands. Co-ligands at the metal ions can be easily substituted by appropriate anions. A specific luminescence response of AMP in presence of ADP, ATP, and other anions is observed. Specificity is assigned to the perfect size match of AMP to bridge the two metal centers and to replace quenching co-ligands in the coordination sphere.

Responsive, Water‐Soluble Europium(III) Luminescent Probes

“…In general the affinity order, determined by the charge of the phosphate moiety, is usually found to be ATP>ADP>AMP, and a different order of selectivity between these species remains a challenge. With this in mind, Albrecht [29] has studied a coordinatively unsaturated double--stranded helical dinuclear europium complex [Eu.12] that causes a significant 64--fold increase of luminescence intensity upon binding AMP molecules with selectivity over ATP and ADP, as well as other biologically relevant ions. Two strands of bis(tridentate) diamide ligands encapsulate two Eu 3+ ions, whose coordination spheres are saturated with water molecules and nitrate ions.…”

Three resorcin[4]arene-based lanthanide-coordination polymers with multifunctional photoluminescence sensing properties

“…2b, the emission peaks at 579, 593, 614, 651, and 698 nm correspond to the 5 D 0 / 7 F J (J ¼ 0-4) transitions of the Eu 3+ cations. 35 Notably, the emission spectrum of 2 is mainly dominated by the 5 D 0 / 7 F 2 transition, which is more intense than others, leading to intense red luminescence. 36 The bright colors also demonstrate that HL 7À acts as an excellent "antenna" linker in the effectively transfer energies to Tb 3+ and Eu 3+ metals.…”

Monitoring of the ADP/ATP Ratio by Induced Circularly Polarised Europium Luminescence

“…[3] Am ore recent example of al uminescent probe capable of monitoring the ADP/ATP ratio on the basis of small molecules was reported by Butler and co-workers,who used ae uropium complex with a1 ,4,7,10-tetraazacyclododecane-1,7-diacetic acid (DO2A)-based ligand bearing two quinolone-derived chromophores to stabilise nucleotide molecules through hydrogen bonding. [5,6] Different strategies to modulate selectivity and binding affinities have been employed, including steric complementarity, [7] variation of the overall charge, [8] and introduction of stabilising and orienting weak interactions,such as hydrogen bonding, [9] p-p stacking, [10] or boroncarbohydrate interactions. [5,6] Different strategies to modulate selectivity and binding affinities have been employed, including steric complementarity, [7] variation of the overall charge, [8] and introduction of stabilising and orienting weak interactions,such as hydrogen bonding, [9] p-p stacking, [10] or boroncarbohydrate interactions.…”

“…[4] Europium complexes have been used extensively for selective anion binding,o ften generating ar atiometric response in emission. [5,6] Different strategies to modulate selectivity and binding affinities have been employed, including steric complementarity, [7] variation of the overall charge, [8] and introduction of stabilising and orienting weak interactions,such as hydrogen bonding, [9] p-p stacking, [10] or boroncarbohydrate interactions. [11] Furthermore,t he high rotatory strength [12] of certain magnetic-dipole allowed transitions in Eu 3+ complexes can give rise to as trong circularly polarised luminescence (CPL) signal, with adissymmetry factor (g em )of up to 1.4.…”