The research has been carried out to identify and evaluate the human factors affecting the operational performance of innovation hubs. The authors conduct a systematic review of relevant literatures and identify certain factors that found to affect the operating performance of Innovation hubs. Through a quantitative research methodology, such as a structured questionnaire, the authors gathered responses from HR experts in the form of an online survey. The survey responses were analyzed with the help of factor analysis, which helped the authors gather 2 components out of 14 survey variables. With the help of factor analysis, the authors developed a model for enhancing the operational performance of innovation hubs. The model can act as a template for further research in the field. Companies can utilize this model for enhancing the operational performances of their innovation hubs.