A recent meta-analysis indicated that 22.9% of adolescents across the globe report having engaged in nonsuicidal self-injury (NSSI) at least once in their lifetime and 18.6% report having engaged in NSSI in the past 12 months (Gillies et al., 2018). Although distinct from suicide behavior, NSSI is a strong risk factor for attempting suicide (Castellví et al., 2017). The World Health Organization (2018) has identified suicide as a public health priority, citing as a key fact that suicide is the second leading cause of death worldwide among 15-to 29-year-olds. This issue of Clinical Child Psychology and Psychiatry (CCPP) includes two articles that examine NSSI over time and one article that examines suicide attempts over time, all among clinical samples of adolescents in the United States, where 17.6% of adolescents in secondary school report having engaged in NSSI in the past 12 months (Monto, McRee, & Deryck, 2018) and suicide is the second leading cause of death not only among ages 15-29 but also among 10-to 14-year-olds (Centers for Disease Control and Prevention, 2017). One common myth about NSSI is that adolescents who self-injure will "grow" out of the behavior, as if it is a phase or a fad (Lewis, Mahdy, Michal, & Arbuthnott, 2014). On the contrary, research has suggested that NSSI often persists into adulthood and that many adults who engage in NSSI began self-injuring when they were teenagers (Klonsky, 2011). In this issue of CCPP, Adrian, Zeman, Erdley, Whitlock, and Sim (2019) longitudinally explore changes in the frequency of NSSI among a group of teenage girls initially admitted to a psychiatric inpatient program. Their study reveals that few participants ceased NSSI over the 2.5-year study, and the majority of those who had not engaged in NSSI at the outset of the study had begun engaging in NSSI by the end of it. There was also a significant increase in NSSI frequency over time, predicted by greater difficulty with emotion regulation and internalizing symptoms. In a second article in this issue of CCPP, Taliaferro, Almeida, Aguinaldo, and O'Brien (2019) use in-depth qualitative interviews to explore self-reported changes in NSSI over time among a group of predominantly female adolescents admitted to a psychiatric inpatient program following a suicide attempt. Their analysis of interviews reveals that, although many participants denied any relationship between their NSSI and suicide attempt, more than half noted that NSSI eventually stopped serving a helpful purpose and subsequently left them feeling the need for something more, as if suicide was the natural next step. If NSSI tends to remain stable among clinical samples of adolescents or even worsen over time, and if NSSI tends to either change function or lose effectiveness as a coping strategy over time among some youth and significantly increase risk for suicide, when is the best time to intervene