Copper and zinc concentrations in serum of healthy Greek adults

Kouremenou-Dona, Eleni; Dona, Artemis; Papoutsis, John; Spiliopoulou, Chara

doi:10.1016/j.scitotenv.2005.04.009

Cited by 38 publications

(28 citation statements)

References 28 publications

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“…In serum, it has been documented for Cu by Ghayour-Mobarhan et al (2005) and Kouremenou-Dona et al (2006); for Se by Lopes et al (2004). In brain, Markesbery et al (1984), Ongkana et al (2010) and Tohno et al (2010)  data converted from nmol/L Table 6.…”

Section: Agementioning

confidence: 99%

Minor and Trace Elements in Cerebrospinal Fluid of Parkinson's Patients – Suggestions After a Critical Review of the Analytical Data

Speziali¹,

Casa²

2011

Diagnostics and Rehabilitation of Parkinson's Disease

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Section: Agementioning

confidence: 99%

Minor and Trace Elements in Cerebrospinal Fluid of Parkinson's Patients – Suggestions After a Critical Review of the Analytical Data

Speziali¹,

Casa²

2011

Diagnostics and Rehabilitation of Parkinson's Disease

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“…The role of zinc as an essential element (8 to 15 mg/day in humans) for immune functioning, DNA synthesis, and enzyme activity is well known [8][9][10]. Also, extensive use of both the metals in pharmaceutical, electroplating, and paint industries increases its concentration in water, air, and soil [11].…”

Section: Introductionmentioning

confidence: 99%

Acyclic Arylamine-Based Ionophores as Potentiometric Sensors for Zn2+ and Ni2+ Ions

Kaur

Chhibber

Mittal

2017

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Abstract:Two receptor molecules N-(2-nitrophenyl)benzene-1,2-diamine (DPA) and N,N-bis(2-nitrophenyl)benzene-1,2-diamine (TPA) are proposed as Zn 2+ and Ni 2+ -selective electrodes, respectively. The two electrodes respond to Zn 2+ and Ni 2+ ions with the detection limits of 1.3 × 10 −6 M and 2.8 × 10 −6 M, respectively. Both the electrodes have a life time of four months and respond within 15 s and 20 s, respectively, for Zn 2+ and Ni 2+ over a wide pH range (3-9). The electrodes show very good selectivity towards the primary ions in presence of some alkali, alkaline earth, and transition metal ions.

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“…erum trace elements, especially Cu and Zn, are critically important in the human body and Cu and Zn serum levels change over the course of various diseases, including malignancy, diabetes, hypertension, gastric ulcer, psychoses, cirrhosis and infectious diseases. [1][2][3][4][5][6][7][8][9] In the human body, these elements are an important components of many metalloenzymes. Acute phase reactants, infections and/or inflammation lead to elevated serum Cu levels and decreased serum Zn levels via cytokines, especially interleukin-1.…”

mentioning

confidence: 99%

“…4,5 The alterations in these trace elements result from the non-specific immune defense mechanisms in the human body. [1][2][3][4][5][6][7] An increased serum Cu/Zn ratio has been reported to be used as an indicator for infectious diseases before development of clinical disease. 4,5,12 Different studies have investigated the diagnostic value or metabolic alterations of Cu and Zn, particularly in infectious diseases.…”

mentioning

confidence: 99%

Alterations of Serum Copper and Zinc Levels, and Copper/Zinc Ratios Among Patients with Brucellosis

Üstün¹,

Teğin²,

Geyik³

2012

Turkiye Klinikleri J Med Sci

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A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To determine the alterations of serum copper (Cu) and zinc (Zn) levels and Cu/Zn ratio in patients with brucellosis. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : A total of 170 individuals were included in the study. Of these, 45 (26.5%) currently had acute or sub-acute brucellosis, 35 (20.6%) were previously diagnosed with acute or sub-acute brucellosis and successfully treated, and 90 (52.9%) were healthy volunteers. After fasting overnight for 10 hours, 5 ml of venous blood was taken.from all subjects. Serum Cu and Zn levels were measured using a Unicam 929 Atomic Absorption Spectrophotometer. SPSS 16.0 was used for data analysis. R Re es su ul lt ts s: : Mean serum Cu levels of 45 patients with acute or sub-acute brucellosis, 35 patients previously diagnosed with acute or sub-acute brucellosis and 90 healthy volunteers were 88.6±26, 58.7±13 and 56.7±16 µg/dL, respectively. Mean serum Zn levels of 45 patients with acute or sub-acute brucellosis, 35 patients previously diagnosed with and treated successfully for acute or sub-acute brucellosis and 90 healthy volunteers were 38.3±12, 58.5±14, and 55.8±13 µg/dL, respectively. Serum Cu levels (p<0.001) and Cu/Zn ratios (p<0.001) were statistically significantly higher while serum Zn levels (p<0.001) were lower in patients with acute or sub-acute brucellosis when compared to the individuals who previously diagnosed with acute or sub-acute brucellosis and the healthy volunteers. C Co on nc cl lu us si io on n: : This study revealed significant alterations of serum Cu and Zn levels, and Cu/Zn ratios in patients with acute or sub-acute brucellosis. Serum Cu, Zn, and Cu/Zn ratios may be available biomarkers in the course of acute or sub-acute brucellosis.K Ke ey y W Wo or rd ds s: : Brucellosis; copper; zinc; trace elements; serum; biological markers Ö ÖZ ZE ET T A Am ma aç ç: : Brusellozlu hastalarda serum bakır (Cu) ve çinko (Zn) düzeylerinde ve bakır/çinko oranlarındaki değişiklikleri saptamaktır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: Çalışmaya toplam 170 birey alındı. Bunların 45'i (26,5%) akut veya sub-akut bruselloz hastası, 35'i (20,6%) daha önce akut veya subakut bruselloz tanısı aldıktan sonra başarılı bir şekilde tedavi edilmiş hastalar ve 90'ı (52,9%) sağlıklı gönüllüler idi. Tüm deneklerden 10 saatlik gece açlığını takiben 5 ml venöz kan alındı. Serum Cu ve Zn düzeyleri Unicam 929 Atomik Absorbsiyon Spektrofotometresi ile ölçüldü. Verilerin incelenmesinde SPSS 16.0 kullanıldı. B Bu ul lg gu ul la ar r: : Akut veya sub-akut brusellozlu 45 hastanın, daha önce akut veya sub-akut bruselloza yakalanan 35 hastanın ve 90 sağlıklı gönüllünün ortalama serum Cu düzeyleri sırasıyla 88,6±26, 58,7±13 ve 56,7±16 µg/dL idi. Akut veya sub-akut brusellozlu 45 hastanın, daha önce akut veya sub-akut bruselloza yakalanan 35 hastanın ve 90 sağlıklı gönüllünün ortalama serum Zn düzeyleri sırasıyla 38,3±12, 58,5±14, ve 55,8±13 µg/dL idi. Daha önce akut veya sub-akut bruselloza yakalananlarla ve s...

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Copper and zinc concentrations in serum of healthy Greek adults

Cited by 38 publications

References 28 publications

Minor and Trace Elements in Cerebrospinal Fluid of Parkinson's Patients – Suggestions After a Critical Review of the Analytical Data

Minor and Trace Elements in Cerebrospinal Fluid of Parkinson's Patients – Suggestions After a Critical Review of the Analytical Data

Acyclic Arylamine-Based Ionophores as Potentiometric Sensors for Zn2+ and Ni2+ Ions

Alterations of Serum Copper and Zinc Levels, and Copper/Zinc Ratios Among Patients with Brucellosis

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