Copper-based metal coordination complexes with Voriconazole ligand: Syntheses, structures and antimicrobial properties

Resurgence and Repurposing of Antifungal Azoles by Transition Metal Coordination for Drug Discovery

“…The same eight fungal organisms were selected for the biological assays, in which the Cu(II) compounds 119-121 gave similar results to those of 118 (Table 4). In particular, 119 displayed the best antifungal activity, especially against C. neoformans, A. niger and A. flavus [94].…”

Therapeutic Effect of Cu(II) Complex with Photocatalytic Property on Gastric Cancer by Inhibiting the Proliferation of Tumor Cells

“…On the other hand, copper is an essential trace metal element in the human body. Modern medical research shows that copper complexes can produce antibacterial, antiviral, anti-inflammatory, antitumor, enzyme inhibitory, or chemical nuclease activities, which are increasingly attracting the attention of researchers [14][15][16]. Another drive for targeting copper(II) was due to its less toxic nature, which can be further decreased on complexation with ligands and thus proved to be promising in the development of copper complexes as anticancer agents.…”

Two coordination polymers: Crystal structures, prevention and nursing values on postoperative infection

“…,2) the carboxyl groups of CPs can be coordinated in many ways, which makes it possible to establish the CPs having outstanding performances and fresh architectures, and (3) the conjugated aromatic rings of CPs are conducive to electron transport and the interactions of π-π with the bioactivity molecules, which might endow them with interesting bioactivity. [16][17][18][19][20] In this current work, two fresh transition metal coordination polymers (CPs) have been created with the reaction between terphenyl-3.3 00 ,5.5 00 -tetracarboxylic acid (H 4 L, Scheme 1), the symmetrical rigid carboxylic acid ligand and the relevant metal salts under the reaction conditions of solvothermal, and the chemical compositions of the compounds respectively are {[Cu 2 (TPTC) (DMF) 2 (H 2 O)]Á2DMFÁ2H 2 O} (2) and {[Zn (TPTC) (1,2-bimb) 2 ]Á 4(H 2 O)} n (1). After providing the novel compounds having new architecture, their prevention and nursing values on postoperative infection was explored and the related mechanism was discussed as well.…”