Copper-catalyzed decarboxylative Se insertion coupling of indoles and propiolic acids

CuBr2-Catalyzed Annulation of 2-Bromo-N-Arylbenzimidamide with Se/S8 Powder for the Synthesis of Benzo[d]isoselenazole and Benzo[d]isothiazole

“…As is known to all, selenium powder is prone to undergo a self-disproportionation reaction to get a selenide anion and selenite in the presence of a base . Based on the aforementioned studies and some related reports, a proposed catalytic cycle (Scheme ) could start with an oxidative addition of 1a with CuX, followed by ligand exchange with Se 2– to generate intermediate III . Then, reductive elimination of III will generate arylselenium anion IV , which reacts with CuX to form the ArSeCu species V .…”

Electrochemical Oxidative Cross-Coupling Reactions of Ketene Dithioacetals and Dichalcogenides to Construct C−Se/C−S Bonds

“…[1][2][3][4][5] Many compounds containing C−S/C−Se bonds have gained much attention in pharmaceutical and biological applications because of their extensive use as therapeutically active agents such as antimicrobial, antioxidant, antiviral, and anticancer agents. [6][7][8][9][10][11] In particular, tetrasubstituted alkenyl selenides and sulfides, as a class of valuable synthetic intermediates and therapeutic entities, have been reported to be ubiquitous in bioactive compounds and natural products. [12][13][14][15] Due to the importance of these structures, a large number of synthetic strategies have been developed in recent years.…”

Divergent Trideuteromethylthiolation and Aminotrideuteromethylthiolation of Alkenes with N-Fluorobenzenesulfonimide and CD3SSO3Na

“…NFSI has been utilized as an amination reagent in the aminative difunctionalization of alkenes; therefore, we were interested in investigating the feasibility of the formation of alkyl trideuteromethyl sulfides with the same substrates by controlling the catalytic system (Table ). Based on our previous research experience in alkene aminothiolation, different copper salts were chosen as catalysts; however, only trace target product 5a was obtained (entry 1). Inspired by Ye’s work on cobalt-catalyzed difunctionalization of alkenes, we started to use cobalt salts as catalysts.…”