Copper‐Catalyzed Simultaneous Installation of Boryl and Carbonyl Functionalities to Unsaturated Hydrocarbons

Abstract

Cu-catalyzed borylative functionalization of unsaturated hydrocarbons is an effective method for synthesizing various organoboron compounds under mild reaction conditions. In particular, installing carbonyl functionalities such as acyl, formyl, and carboxy groups is interesting because of the essential role of these functionalities in organic synthesis. This review focuses on the installation of boryl and carbonyl functionalities in unsaturated hydrocarbons using Cu catalysts. First, formylation and acylation reactions using formate esters, acyl halides, or acid anhydrides are addressed. Second, the simultaneous incorporation of a boryl group and a carboxy group using carbon dioxide as the electrophile is summarized. Third, the borocyanation of unsaturated hydrocarbons using electrophilic cyanation reagents is described.

Recent Advances in the Synthesis of Fused Heterocyclic Compounds and Their Antitumor Activities

“…和烃官能化反应、过渡金属催化不饱和烃不对称反应以 及无金属催化不饱和烃自由基反应等 [12][13][14][15][16] . 但关于过渡 金属介导下由不饱和烃合成稠杂环的综述仍鲜有报道, 因此本文将重点介绍近年来过渡金属催化不饱和烃环 化反应构建稠杂环化合物, 并对机理进行讨论.…”