Copper caused reproductive endocrine disruption in zebrafish (Danio rerio)

Cao, Jianhua; Wang, Guodong; Wang, Tianyu; Chen, Jianjie; Guo, Wei; Wu, Panhong; He, Xinjin; Xie, Lingtian

doi:10.1016/j.aquatox.2019.04.003

Cited by 52 publications

(29 citation statements)

References 53 publications

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“…10 For example, Cu toxicity in fish species results in alteration of their growth and reproductive system, whereas substantial reduction in algal biomass and shift in algal communities are observed with increased Cu concentrations in freshwater lakes. 11–14…”

Section: Introductionmentioning

confidence: 99%

The role of organic colloids in the sequestration and mobilization of copper in smelter-impacted soils

Jadoon

Schindler

2022

Environ. Sci.: Processes Impacts

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Section: Introductionmentioning

confidence: 99%

The role of organic colloids in the sequestration and mobilization of copper in smelter-impacted soils

Jadoon

Schindler

2022

Environ. Sci.: Processes Impacts

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“…Several metals have been identified as potentially harmful pollutants to the fish reproductive system due to their destruction of the hypothalamic-pituitary-gonadal axis or other endocrine centers (Iavicoli et al 2009), alteration of the mechanism of hormone biosynthesis, or interference with several hormones and their receptors (Martyniuk et al 2020). Copper metal has been established to be a reproductive disruptor in zebrafish by injuring the gonads, modifying the steroid hormone concentrations, and the expressions of endocrine-related genes in the hypothalamic-pituitary-gonadal axis (Cao et al 2019). Deepa et al (2019) reported defective testicular lumen, slow progress of spermatogenesis, and increased Leydig cell degeneration in Cyprinus carpi after exposure to different forms and doses of zinc metal.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Exposure to the Water of Wadi El-Rayan Lakes Induced Testicular Damage and Endocrine Disruption in Mugil cephalus

Abdel-Khalek

Al‐Quraishy

Abdel‐Gaber

2021

Bull Environ Contam Toxicol

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This study aimed to investigate the testicular function of Mugil cephalus that inhabit Wadi El-Rayan lakes. Testes of fish inhabiting the upper lake (site 2) and the lower lake (site 3) of Wadi El-Rayan showed significant decreases in gonadosomatic index, high accumulation levels of six metals, and eight organochlorine pesticide residues. Compared to reference fish, high percentages of histological alterations as testicular degeneration, germ cell reduction, testicular inflammation, vacuolization, and loss of tubular arrangement were observed in sites 2 and 3. Moreover, endocrine disruption signs were recorded based on the percentage of ovotestis appearance and the ovotestis severity index values. The maximum defective testicular antioxidant mechanisms were recorded in site 3 as indicated by sharp decreases in catalase, superoxide dismutase, glutathione reduced levels, and high thiobarbituric acid reactive substances. Finally, long-term exposure to Wadi El-Rayan water may impair the reproductive health of fish via testicular oxidative damage and endocrine disruption.

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“…Hasil penelitian Aziz et al, (2017) menunjukan pengaruh akumulasi merkuri (Hg) pada gonad mengakibatkan lisis atau nekrosis. Nekrosis atau kematian sel pada ovary yang merupakan organ reproduksi pada ikan betina dapat mengancam keberlanjutan populasi ikan karena pada dasarnya reproduksi merupakan faktor kunci dalam mempertahankan populasi ikan (Ojaveer et al, 2015;Cao et al, 2019). Gambar 4.…”

Section: Pengaruh Merkuri (Hg) Pada Jaringan Ikanunclassified

Toksisitas Merkuri (Hg) pada struktur jaringan ikan

Ibrahim¹,

Aris²

2020

e-BDP

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The problem of pollution that occurs in the aquatic environment is getting out of control and causes the degradation of fishery resources which are important for humans. One of the pollutants from industrial activities is heavy metal. There are various kinds of heavy metals, mercury (Hg) is the most dangerous heavy metal. Mercury (Hg) enters directly into the waters through rainwater and leaching the soil and river flows which are then absorbed and metabolized by microorganisms. Mercury (Hg) is difficult to degrade from the body, because mercury (Hg) is actively involved in the food chain. Microorganisms feed molluscs, crustaceans and fish which are a source of protein for humans. Mercury (Hg) toxicity in fish can result in a stress response in fish which results in impaired growth, immune system, and changes in tissue structure. This brief review aimed to enrich the scientific repertoire of the toxicity of mercury (Hg) in fish and its effects on humans. This review was a non-experimental research by conducting research around the literature

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Copper caused reproductive endocrine disruption in zebrafish (Danio rerio)

Cited by 52 publications

References 53 publications

The role of organic colloids in the sequestration and mobilization of copper in smelter-impacted soils

The role of organic colloids in the sequestration and mobilization of copper in smelter-impacted soils

Long-Term Exposure to the Water of Wadi El-Rayan Lakes Induced Testicular Damage and Endocrine Disruption in Mugil cephalus

Toksisitas Merkuri (Hg) pada struktur jaringan ikan

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