Copper complexes bearing methylthiophenyl and methylfuranyl derivatives of (R,R)-1,2-diaminocyclohexane: X-ray structures and catalytic exploitation in Henry reaction

Synthesis and structures of copper complexes bearing unsymmetric derivatives of (R,R)‐1,2‐diaminocyclohexane: An efficient catalyst for asymmetric Henry reaction

“…The Cl1–Cu–Cl2 angle of 95.70(6)° is much larger than the 83.85(14)° N1–Cu–N2 angle of [L 3 CuCl 2 ] . These angles are smaller than we previously reported for the same ligand . The N1–Cu–Cl2 and N2–Cu–Cl1 angles were 94.3(1)° and 93.3(1)°, respectively.…”

“…However, the induced nitrogen chirality in the two asymmetric units in [L 4 CuCl 2 ] 2 was R N , R N and R N , S N . Such a diastereomeric configuration in two asymmetric units of a dimer is rarely observed . Figure shows that this selective R , S ‐coordination of one asymmetric unit of the dimeric structure is due to the pseudo‐axial orientation of the benzyl moiety at N1, and to pseudo‐equatorial orientation of the anthracene moiety at N2.…”

“…Further, the asymmetrical ligand framework represents an attractive option because of its diverse structural properties . The potential merits of the ( R , R )‐1,2‐diaminocyclohexane framework and recent promising results in the asymmetric Henry reaction for Cu (II) complexes supported by such ligands, as reported by our group, encouraged us to evaluate asymmetrical chiral diamines based on the ( R , R )‐1,2‐diaminocyclohexane backbone . Although impressive progress has been achieved, there remains a need for new catalysts for the asymmetric Henry reaction of aldehydes with nitromethane.…”

Synthesis, crystal structure, Hirshfeld surface analysis, and vibrational and DFT investigation of [C6H10(NH3)2]3CuBr4.3Br

“…The crystal structure of the title compound was solved in a trigonal subcell (P, a = 15.8494 (19) Å, c = 7.4243(9) Å). The asymmetric unit of the title compound shown in Fig.…”

“…Recently, the 1,2-diaminocyclohexane molecule has been used in combination with different metal transitions such as Ni, Zn, Cu, and Fe to characterize a new complexes class containing organic and inorganic parts [19][20][21][22].…”