Copper complexes: cytotoxicity and transport possibilities

Specific features of sorption of bovine serum albumin on hydroxyapatite doped with zinc ions, and the possibilities of its use as an intermediate binding protein for heterocyclic ligands

“…Metal organic complexes have the same properties, and, in this case, the ligand also undergoes transchelation with calcium ions. 8 In the body, albumins, namely, human serum albumin (HSA) and bovine serum albumin (BSA), have a transport function, therefore, they can probably serve as an intermediate binding protein between organic ligands and carriers, which can be modifi ed HAP nanoparticles, for example, HAP pre-doped with zinc ions (HAP-Zn). 9 This modifi cation of the sorbent helps to create additional coordination centers on the surface of nanoparticles and, at the same time, assists the preliminary replacement of mobile calcium ions with zinc ions to prevent (or slow down) overchelation.…”