Copper-cysteamine nanoparticles encapsulating fluorocoumarin silicon(IV) phthalocyanines: synthesis, characterization, and photophysical properties

Graphene Oxide/Cholesterol-Substituted Zinc Phthalocyanine Composites with Enhanced Photodynamic Therapy Properties

“…In line with this, Ф of the GO/Chol-ZnPc c posite (Ф = 0.36) was, indeed, higher than that of both Chol-ZnPc (Ф = 0.31) and substituted ZnPc, as listed in Table 1. The singlet oxygen quantum yield (Ф ) was determined in DMSO via a comm method [77][78][79][80][81][82] by using 3-diphenylisobenzofuran (DPBF) as a singlet oxygen scaven The singlet oxygen quantum yield (Φ ∆ ) was determined in DMSO via a common method [77][78][79][80][81][82] by using 3-diphenylisobenzofuran (DPBF) as a singlet oxygen scavenger and unsubstituted ZnPc as a standard. As is known, DPBF does not decompose with singlet oxygen; instead, its reaction with singlet oxygen causes a decrease in the absorbance intensity at 417 nm, which could be used to measure the singlet oxygen generation ability [78].…”

Chlorophenyl thiophene silicon phthalocyanine: Synthesis, two-photon bioimaging-guided lysosome target, and in vitro photodynamic efficacy

“…The most common PDT strategies are photo-damage of the mitochondria and lysosomes. In particular, lysosomes have attracted attention because they are involved in the maintenance of cellular homeostasis and regulation or interaction with other organelles ( Liu et al, 2010 ; Zou et al, 2017 ; Chen et al, 2019 ). The induction of cancer cell programmed necrosis by nano-drugs with lysosome-targeting capability has been reported and has become a hot topic for overcoming cancer resistance to apoptosis and therapy ( Yu et al, 2012 ; Meng et al, 2019 ).…”