Copper Deficiency a New Reason of Androgenetic Alopecia?

Skalnaya, Margarita G.

doi:10.5772/58416

Cited by 6 publications

(3 citation statements)

References 14 publications

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“…Previously, Cu de ciency has been shown to be signi cant in other forms of alopecia, particularly in AGA [8] and AA [13]. Moreover, it has been indicated that disturbances in Cu metabolism play a key role in AGA onset [14,15]. Since Cu is an essential trace element for hair formation and regeneration [16], the development of post-COVID-19 alopecia under conditions of its de ciency becomes quite explicable.…”

Section: Discussionmentioning

confidence: 99%

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Assessment of selective elements in serum and hair samples of women with post-COVID-19 alopecia: copper significance

Kondrakhina,

Kondrakhin,

Nikonorov

et al. 2024

Preprint

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Hair loss is an unexpected but fairly common complication after recovering from COVID-19. Often, it is the only symptom of infection. Trace elements and metals play an important role in the pathogenesis of both pathological hair loss and the COVID-19 – however, the existing data on the development of these conditions are fragmentary and contradictory. The aim of the study was to assess the levels of Ca, Fe, Mg, Se, Cu, and Zn in the serum and hair of women with post-COVID alopecia and their relationship with trichogram data. The study included 40 women aged 25–41 with complaints of hair loss and a history of laboratory-confirmed COVID-19. Levels of calcium (Ca), iron (Fe), magnesium (Mg), selenium (Se), copper (Cu), and zinc (Zn) in serum and hair samples were analyzed using inductively coupled plasma mass spectrometry. The study showed the development of telogen-type alopecia after recovering from COVID-19. The significant decrease in serum Cu levels was characteristic of post-COVID alopecia, however, no correlation with trichological data was found. In hair, the levels of analyzed trace elements were within reference values. A negative correlation between hair Cu and percent of telogen hairs, and a positive correlation with the anagen hairs in the occipital region were found. This study presents, for the first time, evidence of Cu deficiency in cases of post-COVID-19 alopecia. this fact sets the stage for exploring the potential use of Cu in recommended doses for preventing and treating post-COVID-19 alopecia.

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Section: Discussionmentioning

confidence: 99%

“…From a practical viewpoint, incorporating Cu supplements into the management of post-COVID-19 alopecia is feasible. The rationale for this is supported by the experience of using Cu in other types of alopecia [15] and its effects as a prophylactic and therapeutic agent against COVID- 19 [18, 20].…”

Section: Discussionmentioning

confidence: 99%

Assessment of selective elements in serum and hair samples of women with post-COVID-19 alopecia: copper significance

Kondrakhina,

Kondrakhin,

Nikonorov

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…The serum level tend to show the current status of the body, and the hair level showed that long a time limit and can be measured in years. [13] Micronutrient levels in various types of alopecia except androgenic alopecia have been reported and the results are still being debated. The results were varied in levels of copper and zinc in many studies can be explained because the foundation of the sample size, methodology and variations in population.…”

Section: Discussionmentioning

confidence: 99%