Copper (triazole-5-yl)methanamine complexes onto MCM-41: the synthesis of pyridine-containing pseudopeptides through the 6-endo-dig cyclization of 1,5-enynes

Abstract

A sequential Ugi/nucleophilic addition/1,5-enyne cyclization reaction was used for the synthesis of pseudopeptides containing pyridine skeletons in the presence of Cu@TZMA@MCM-41.

Synthesis and characterization of highly efficient and recoverable Cu@MCM-41-(2-hydroxy-3-propoxypropyl) metformin mesoporous catalyst and its uses in Ullmann type reactions

“…for example, Wang et al 11 prepared a series of Sn-containing mesoporous MCM-41 catalysts for the conversion of pyruvaldehyde to ethyl lactate. Multicomponent reactions, such as Ugi 12 , Gewald 13 or coupling reactions 4 , and redox 9 , 14 have also been reported using these functionalized MCM-41 catalysts.…”

Ecofriendly and Facile One‐Pot Multicomponent Synthesis of 5‐Phenyl‐5,10‐dihydropyrido[2,3‐d : 6,5‐d′]dipyrimidine‐2,4,6,8(1H,3H,7H,9H)‐tetraone Derivatives Catalyzed by CuII Immobilized on Functionalized Magnetic Mesoporous MCM‐41 (Fe3O4@MCM‐41‐GPTMS‐Gu‐CuII)

“…This was also preserved in the pattern of Fe 3 O 4 @MCM‐41‐GPTMS‐Gu‐Cu II ( V ) nanocatalyst (Figure 3b), representing the high stability of the structure of the designed nanocatalyst. Notably, compared to the pattern of Fe 3 O 4 @MCM‐41 ( II ), a decreasing intensity peak confirmed functionalization of MCM‐41 channels during preparation steps of Fe 3 O 4 @MCM‐41‐GPTMS‐Gu‐Cu II ( V ) [44] …”

“…The next step happened at 150–250 °C (13 %), which can be attributed to the elimination of organic segments anchored on Fe 3 O 4 @MCM‐41( II ). Finally, the last step, which was at around 250 °C and continued up to 560 °C (12 %), was due to the complete decomposition of the nanocatalyst and silanol groups (Figure 10d) [44,47] . Based on the TGA results, the amounts of organic linkers anchored on Fe 3 O 4 @MCM‐41( II ) was evaluated to be 1 mmol g −1 .…”

“…Notably, compared to the pattern of Fe 3 O 4 @MCM-41 (II), a decreasing intensity peak confirmed functionalization of MCM-41 channels during preparation steps of Fe 3 O 4 @MCM-41-GPTMS-Gu-Cu II (V). [44] The nitrogen adsorption-desorption isotherms and pore size distribution curves of Fe 3 O 4 @MCM-41 (II) and Fe 3 O 4 @MCM-41-GPTMS-Gu-Cu II (V) are presented in Figure 4a-c. As demonstrated in Figure 4a, Fe 3 O 4 @MCM-41 (II) and Fe 3 O 4 @MCM-41-GPTMS-Gu-Cu II (V) exhibited the characteristics of type IV isotherms as reported by the IUPAC classification of adsorption isotherms with H1-type hysteresis loop [45a] (which is a characteristic of ordered mesoporous materials) (Figure 4 a). The specific surface area, pore-volume, and mean pore diameter of Fe 3 O 4 @MCM-41 (II) and Fe 3 O 4 @MCM-41-GPTMS-Gu-Cu II (V) are shown in Table 1.…”

“…Finally, the last step, which was at around 250°C and continued up to 560°C (12 %), was due to the complete decomposition of the nanocatalyst and silanol groups (Figure 10d). [44,47] Based on the TGA results, the amounts of organic linkers anchored on Fe 3 O 4 @MCM-41(II) was evaluated to be 1 mmol g À 1 . These findings are in perfect accordance with the results obtained from elemental analysis data (N = 1.71 % and C = 4.16 %).…”