Cor pulmonale due to Schistosoma mansoni

Schistosomiasis mansoni: associated hepatosplenic, cardiovascular, and chronic miliary forms

“…6,20 It is assumed that eggs coming from the portal vein arrive at the lungs through the collaterals that form between the porta system and systemic circulation in order to compensate for the increased portal pressure. 8,18 This has been confirmed experimentally. 3,4 It is understandable, therefore, that serious pulmonary lesions may occur, as in fact occur, during the development of the hepatosplenic form through the establishment of communication between the portal and systemic circulation (hepatoscaping routes) that promote direct and continuous drainage of eggs to the right atrium and, consequent-cells; discreet infiltrate of mononuclear cells in the vicinity of the arteriole; granuloma in the exudative phase around a deformed egg in the interstice ( Figure 6); and mild interstitial subcapsular fibrosis.…”

“…Ectopic lesions are considered those caused by worms or eggs outside the portomesenteric system (hepato-intestinal system), habitat of adult Schistosoma mansoni in the human body. [1][2][3][4][5][6][7][8][9][10][11][12] , however, excluded pulmonary arterioles lesions from ectopic sites. The frequency of pulmonary locations varies between the different regions of origin of patients.…”