Cordocentesis

Fetal bradycardia following cordocentesis

“…The increased incidence of bradycardia following puncture of the umbilical artery confirms the hypothesis that the insertion of the needle might cause a spasm of the vascular wall (Weiner et al, 1991b;Bell and Weiner, 1993). On the other hand, bradycardia may occasionally occur due to a reflex, resulting from compression of the umbilical cord due to a haematoma at the insertion site.…”

Fetal heart rate response to cordocentesis and pregnancy outcome: A prospective cohort

“…A reflex response resulting from compression of the umbilical cord due to a hematoma formation at the insertion site might be the cause [5,14,15]. Bradycardia commonly occurs among fetuses with severe early-onset growth restriction or with fetal hydrops [11,14].…”

Genetic diagnostic methods for inherited eye diseases

“…If an earlier diagnosis is necessary, a transabdominal or transvaginal chorionic villus sample can be obtained between 10 and 14 weeks of gestation; however the risk of fetal death related to this approach is twice as high: 1%. If a quick karyotype result is needed during a more advanced gestation (higher than 20 weeks), then a cordocentesis, which carries a chance of 2% to 5% of fetal death, can be performed 6–11. Blood, amniotic fluid and chorionic villi should be kept at room temperature and be transported to the laboratory without delays.…”

“…If a quick karyotype result is needed during a more advanced gestation (higher than 20 weeks), then a cordocentesis, which carries a chance of 2% to 5% of fetal death, can be performed. 6 – 11 Blood, amniotic fluid and chorionic villi should be kept at room temperature and be transported to the laboratory without delays. The specimens are then processed and the chromosome spreads on slides are prepared.…”