Core principles of treatment of corneal damage in patients with thyroid eye disease

Grusha, Y.O.; Ismailova, D S; Sherstneva, L V

doi:10.17116/oftalma2016132535-38

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…Increased palpebral fissure height is recognized as an essential risk factor for the development of tear film instability and ocular surface damage among patients with dysthyroid orbitopathy ( 7 , 15 , 16 ). Moreover, palpebral fissure height in these patients correlates positively with higher tear evaporation rate, increased tear film osmolarity, and significantly lower values of TBUT compared to healthy subjects ( 9 , 10 , 17 , 18 ).…”

Section: Discussionmentioning

confidence: 99%

The Effect of Palpebral Fissure Height in Primary Gaze Position on Tear Film Stability

Čović

2023

ACC

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SUMMARY This study aimed to investigate the effect of palpebral fissure height in primary gaze position in healthy individuals on tear film stability. In this cross-sectional study, 120 subjects (60 male and female each) were enrolled and divided according to age into two groups, i.e., group 1 (aged 18-50 years) and group 2 (aged 51 and older). Palpebral fissure height on both eyes was measured in primary gaze position with a clear plastic ruler held in a central vertical position between the upper and lower lid margin, and the standard tear break-up time (TBUT) test was performed to evaluate tear film stability. Palpebral fissure height was significantly higher in younger than older subjects in all measurements on both eyes (p<0.001), and TBUT was shorter in older than in younger subjects. In all subjects included in the study, palpebral fissure height was not related to TBUT (p=0.589). However, analyzing the two age groups separately, a significant negative correlation was found between the palpebral fissure height and TBUT in both groups of younger (p<0.001) and older (p=0.009) subjects. In conclusion, an enlarged exposed ocular surface due to higher palpebral fissure height in healthy individual’s primary gaze position negatively affects tear film stability expressed by TBUT.

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Section: Discussionmentioning

confidence: 99%

The Effect of Palpebral Fissure Height in Primary Gaze Position on Tear Film Stability

Čović

2023

ACC

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Bony orbital decompression in the treatment of endocrine ophthalmopathy

Ismailova

Grusha

2019

Vestn. oftal'mol.

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В статье проанализирована отечественная и иностранная литература, касающаяся костной декомпрессии орбиты при эндокринной офтальмопатии (ЭОП). Описаны показания к проведению, различные виды декомпрессии орбиты. Проанализированы преимущества и недостатки каждого метода. Отдельно описаны осложнения различных методик, их частота и последствия, а также эффективность. Ключевые слова: костная декомпрессия орбиты, латеральная стенка орбиты, медиальная стенка орбиты, оптическая нейропатия, сбалансированная декомпрессия орбиты, косоглазие.

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Orbital decompression in the system of treatment for complicated thyroid eye disease: case report and literature review

Ismailova¹,

Беловалова

Grusha

et al. 2018

IMCRJ

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Orbital decompression is a surgical procedure aimed at increasing the orbital volume and/or decreasing the volume of the orbital fat. The indications for orbital decompression are determined in the course of thorough eye examination. An important objective of examination of a patient with thyroid eye disease (TED) is determination of inflammation activity and severity. Orbital decompression is a surgical procedure that can be performed in both the active and nonactive stages of the disease. However, the indications for the surgery in these cases are different. Optic neuropathy and severe corneal disease are threatening complications that may lead to permanent visual loss and generally occur in the presence of active orbital inflammation. If treatment with high-dose corticosteroids has proven ineffective, an urgent surgical procedure consisting of orbital decompression and, in case of involvement of the cornea, eyelid and corneal surgery has to be performed. Owing to significant progress in technology, improvement of methods and accumulated experience over the past decade, the indications for bone orbital decompression have extended compared to the time when this procedure was used only in patients with extremely severe TED. The most common complication of the orbital decompression is the development or deterioration of previously existing binocular diplopia and strabismus. In addition, other parameters may change as well, including the position of the globe, the eyelids, the angle of deviation of the eye, and intraocular pressure. Thus, bone orbital decompression is a major step of a comprehensive, often multistage, system of rehabilitation of patients with severe refractory TED.

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Core principles of treatment of corneal damage in patients with thyroid eye disease

Cited by 3 publications

References 8 publications

The Effect of Palpebral Fissure Height in Primary Gaze Position on Tear Film Stability

The Effect of Palpebral Fissure Height in Primary Gaze Position on Tear Film Stability

Bony orbital decompression in the treatment of endocrine ophthalmopathy

Orbital decompression in the system of treatment for complicated thyroid eye disease: case report and literature review

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