Corneal astigmatism in Graves' ophthalmopathy

Mombaerts, Ilse; Vandelanotte, Sylvie; Koornneef, L.

doi:10.1038/sj.eye.6701898

Cited by 18 publications

(19 citation statements)

References 18 publications

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“…Jankauskiene et al revealed that in children with thyroid eye disease and protrusion ≥ 17 mm myopia was noted more often than in control group [36]. Other studies found worsening of previously diagnosed myopia [37] and higher incidence of astigmatism in patients with TAO [38]. Refraction changes in course of thyroid gland diseases may be associated with proliferation of orbital matrix and enlargement of extraocular muscles, which cause remodeling of the eye bulb and elongation of optical axis.…”

Section: Symptoms and Signs Of Thyroidassociated Ophthalmopathymentioning

confidence: 99%

An update on thyroid-associated ophthalmopathy in children and adolescents

Szczapa-Jagustyn¹,

Gotz‐Więckowska²,

Kocięcki³

2016

Journal of Pediatric Endocrinology and Metabolism

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Section: Symptoms and Signs Of Thyroidassociated Ophthalmopathymentioning

confidence: 99%

An update on thyroid-associated ophthalmopathy in children and adolescents

Szczapa-Jagustyn¹,

Gotz‐Więckowska²,

Kocięcki³

2016

Journal of Pediatric Endocrinology and Metabolism

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“…There is evidence that these changes can give rise to astigmatism 1 and raised intraocular pressure (IOP). In addition, the extent of IOP elevation may correlate with the degree of proptosis.…”

Section: Introductionmentioning

confidence: 99%

The effect of orbital decompression surgery on refraction and intraocular pressure in patients with thyroid orbitopathy

Norris

Ross

Kazim

et al. 2012

Eye

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Purpose To investigate the effect of orbital decompression surgery in thyroid orbitopathy (TO) on both refractive status and intraocular pressure (IOP). Patients and methods A prospective, multicentre, consecutive audit of patients undergoing thyroid decompression surgery. Indications for surgery included cosmetically unacceptable proptosis or corneal exposure. Exclusion criteria included the following: previous orbital surgery, glaucoma, corneal disease, steroid use in the preceding 12 months, or an acute optic neuropathy. Automated refraction, keratometry, pachymetry, Hertel exophthalmometry, and IOP were recorded at 1 month pre-and 3 months postoperatively. IOP using the Tono-Pen (mean of three readings) was measured in the primary, upgaze, and downgaze positions. Results Data were collected from 52 orbits of 33 patients (East Grinstead, New York, and Adelaide). There was no significant difference between pre-and postoperative data for sphere, cylinder, or central corneal thickness (CCT). The mean spherical equivalent was À0.43±1.49 D pre-operatively and À0.28±1.52 D postoperatively. The steepest meridian of corneal curvature was 93.1 degrees pre-and 94.2 degrees postoperatively, with no significant difference. Mean IOP significantly decreased when measuring by Goldmann applanation tonometry (GAT) (2.28 mm Hg, *P ¼ 0.001) and Tono-Pen (3.06 mm Hg, *P ¼ o0.0001). IOP measured in upgaze was significantly greater than that in the primary position. Regression analysis between change in IOP and either Hertel exophthalmometry or the number of orbital walls decompressed was non-significant (*Student's t-test). Conclusion Patients with TO undergoing orbital decompression had, on average, with-the-rule astigmatism not affected by orbital decompression surgery. IOP was significantly reduced by decompression surgery although no relationship between IOP and the degree of decompression was observed.

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“…Another study by Mombaerts et al [19] stated that higher degrees of "with the rule astigmatism" were found in patients under 55 years old who suffered Graves' ophthalmopathy. ese patients were examined clinically and by CT and were found to have fibrosis of the orbit as well as restrictive motility disorders.…”

Section: Discussionmentioning

confidence: 99%

The effect of strabismus muscle surgery on corneal biomechanics

Gendy¹,

Khalil²,

Eissa³

et al. 2018

Journal of American Association for Pediatric Ophthalmology and

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is properly cited. Purpose. Studying the early effect of different extraocular muscle (EOM) surgeries on corneal biomechanics. Subjects and methods.is is a prospective, nonrandomized, interventional study, in which 42 eyes of 29 candidates for EOM surgery for strabismus correction at Cairo university hospitals, aged 14-37 years, were recruited. All participants had measuring of the visual acuity, refraction (spherical equivalent (SE)), assessment of the EOM motility and muscle balance, sensory evaluation, fundus examination, and assessing the ocular biomechanics using the Ocular response analyzer (ORA, Reichert, INC., Depew, NY) noting the corneal hysteresis (CH) and corneal resistance factor (CRF) preoperatively. Same patients were reassessed using ORA 4 weeks postoperatively following a different standard EOM surgery (recti weakening/strengthening and inferior oblique weakening either (graded recession) according to the surgical indication, and ∆CH and ∆CRF were calculated, each is the preoperative − the postoperative value. Results. ∆CH and ∆CRF � −0.78 ± 1.56 and −0.72 ± 2.15, respectively, and a highly significant difference was found between each of the pre-and postoperative CH and CRF (p < 0.001). 18 eyes had single EOM surgery, while 24 had multiple (2 or 3) EOM surgery; ∆CH in the single group � 1.28 1.5, and ∆CH in the multiple group � 0.4 1.49 (p � 0.07). 23 eyes had EOM weakening surgery, while 18 had combined weakening and strengthening EOM surgery: ∆CH in the weakening group � 1.24 1.77 and ∆CH in combined group � 0.26 1.07 (p � 0.04). A nonsignificant difference was found for ∆CRF (p � 0.53). Conclusion. A different EOM surgery has an early tendency for increase of the postoperative CH specially for muscle weakening procedures (recti recession/inferior oblique muscle weakening).

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Corneal astigmatism in Graves' ophthalmopathy

Cited by 18 publications

References 18 publications

An update on thyroid-associated ophthalmopathy in children and adolescents

An update on thyroid-associated ophthalmopathy in children and adolescents

The effect of orbital decompression surgery on refraction and intraocular pressure in patients with thyroid orbitopathy

The effect of strabismus muscle surgery on corneal biomechanics

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