Corneal Complications Associated with the Use of Crack Cocaine

Sachs, Ronald; Zagelbaum, Bruce M.; Hersh, Peter S.

doi:10.1016/s0161-6420(93)31672-6

Cited by 51 publications

(47 citation statements)

References 8 publications

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“…Consultation with an ophthalmologist is recommended, and empiric antibiotic eye drops should be started after cultures have been obtained. As noted in previous case series, poor compliance may make admission necessary to adequately ensure appropriate treatment (2).…”

Section: Discussionmentioning

confidence: 90%

Crack Eye

Miller¹,

Sherman²

2009

The Journal of Emergency Medicine

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Section: Discussionmentioning

confidence: 90%

Crack Eye

Miller¹,

Sherman²

2009

The Journal of Emergency Medicine

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“…In 1989, McHenry et al (9) first described corneal epithelial defects that were associated with crack cocaine. Since then, others have reported regarding corneal damage caused by narcotics (3)(4)(5) . This is the first case that is associated with anterior staphyloma.…”

Section: Discussionmentioning

confidence: 99%

“…There are many possible mechanisms by which corneal complications resulting from crack cocaine may develop (4)(5) . Cocaine can exert a direct toxic effect on the cornea by damaging epithelial plasma membranes and microvilli, or the repeated exposure to cocaine may result in decreased corneal sensation and poor blink reflex; moreover, the alkaline nature of crack cocaine could cause low-grade chemical burns to the cornea.…”

Section: Discussionmentioning

confidence: 99%

“…Acquired anterior staphyloma occurs subse quent to corneal perforation, usually following untreated or non-responding infective keratitis (1) .Anterior staphylomas are rarely observed in patients with Peters anomaly (2) . Various ocular complications that are associated with crack cocaine have been reported, including epitheliopathy, microbial keratitis, and corneal perforation (3)(4)(5) . Such manifestations result from many factors, ranging from direct drug effects to the social environment of the patient.…”

Section: Introductionmentioning

confidence: 99%

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Acquired anterior staphyloma after corneal ulcer associated with the use of crack

Vasconcelos

Guerra

Morato

et al. 2016

Arquivos Brasileiros De Oftalmologia

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CASE REPORTA 30-year-old black man presented with a 4-week history of a foreign body sensation, redness, and pain in his right eye. His left eye was stable. The patient had a history of crack cocaine and injected heroin abuse. He was homeless and admitted to using crack cocaine daily over the past 4 months. He denied any previous contact lens use, trauma, or ocular surgery. He was otherwise quite well with no systemic symptoms, and his general medical history was unremarkable.On examination at our hospital, uncorrected visual acuity was found to be light perception (LP) in the right eye and 20/25 in the ABSTRACTWe describe an unusual case of acquired anterior staphyloma in a patient addicted to crack cocaine. At the beginning of his crack cocaine abuse, he noticed redness and irritation of his eyes. Over the next 4 months, the patient also noticed the onset of decreasing visual acuity in his right eye (OD). Initially, his visual acuity was light perception in OD, and slit-lamp examination revealed a corneal infiltrate with a peripheral perforation and an iris prolapse. The patient was hospitalized to ensure compliance with the prescribed treatment and was advised to undergo therapeutic keratoplasty; however, the patient left the hospital against medical advice and was lost to follow-up for the next 6 months. He returned with complaints of photophobia and the inability to close his right eyelids. At this time, his cornea had developed an anterior staphyloma and required a sclerokeratoplasty. Following surgery, the patient was again lost to follow-up.

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“…Decreased corneal sensitivity, the direct toxic effect of the smoke, neurotrophic changes, or vigorous eye rubbing have all been suggested as leading to corneal problems in crack cocaine users, which may include corneal ulcers, superficial punctate keratitis, and corneal epithelial defects. 11 Cocaine powder may be introduced into the eye in error by contact lens wearers. 12 Previously in Eye, 13 I reported the onset of esotropia following heroin withdrawal and this has since been reported by others.…”

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confidence: 99%

Class A drug abuse: an ophthalmologist's problem?

Firth

2005

Eye

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Corneal Complications Associated with the Use of Crack Cocaine

Cited by 51 publications

References 8 publications

Crack Eye

Crack Eye

Acquired anterior staphyloma after corneal ulcer associated with the use of crack

Class A drug abuse: an ophthalmologist's problem?

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