Corneal edema after cataract surgery: Incidence and etiology

Yi, David H.; Dana, M. Reza

doi:10.1076/soph.17.3.110.14783

Cited by 49 publications

(34 citation statements)

References 24 publications

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“…Application of honey to intact control corneas did not elicit any such anti‐inflammatory response . Post‐operative inflammation has been identified as a cause of persistent post‐operative corneal oedema following cataract surgery . Persistent corneal inflammation and vascularisation increase the risk of corneal graft rejection after keratoplasty for post‐operative corneal decompensation .…”

Section: Discussionmentioning

confidence: 98%

“…Honey was used adjunctive to the conventional management of persistent post‐surgical corneal oedema. Initial treatment of post‐operative oedema involves addressing the surgically and medically treatable causes, such as inflammation, infection, elevated intraocular pressure, intraocular lens misalignment, retained lens fragments and Desçemet's membrane detachment . Topical penetrating corticosteroids, such as prednisolone acetate one per cent, may be required to treat persistent anterior chamber inflammation (Table , Cases 3, 5, 7 and 18).…”

Section: Discussionmentioning

confidence: 99%

“…Topical broad‐spectrum antibiotic prophylaxis and close monitoring are recommended in cases of epithelial breakdown associated with bullous keratopathy due to an increased risk of microbial keratitis. Hypertonic agents, such as five per cent hypertonic sodium chloride (for example, Muro 128, Bausch & Lomb, Bridgewter, New Jersey, USA) (Table Cases 2, 5, 7, 9 and 11) may have a marginal transient benefit in reducing corneal oedema due to a relatively weak hyperosmotic effect, Topical compounded anhydrous glycerine can have a rapid (within two minutes) but transient, hyperosmotic effect on corneal oedema; however, topical glycerine is unsuitable for chronic use due to the absence of an approved topical glycerine product and considerable stinging, injection and photophobia on instillation …”

Section: Discussionmentioning

confidence: 99%

“…Despite advances in surgical techniques, corneal oedema is one of the most common complications of cataract surgery . Most post‐operative corneal oedema is transient and subsides within the first days or weeks after surgery; however, in some cases, corneal oedema can be protracted and if sufficient endothelial cell loss occurs, irreversible pseudophakic bullous keratopathy results . Persistent corneal oedema or corneal decompensation following cataract surgery occurs in approximately 0.5 per cent of cases .…”

mentioning

confidence: 99%

“…Most post‐operative corneal oedema is transient and subsides within the first days or weeks after surgery; however, in some cases, corneal oedema can be protracted and if sufficient endothelial cell loss occurs, irreversible pseudophakic bullous keratopathy results . Persistent corneal oedema or corneal decompensation following cataract surgery occurs in approximately 0.5 per cent of cases . In a high‐volume cataract surgical clinic, a case of persistent post‐operative corneal oedema would be expected to be encountered every few months.…”

mentioning

confidence: 99%

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Standardised antibacterial Manuka honey in the management of persistent post‐operative corneal oedema: a case series

Albietz

Lenton

2015

Clinical and Experimental Optometry

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Background: Corneal oedema is a common post-operative problem that delays or prevents visual recovery from ocular surgery. Honey is a supersaturated solution of sugars with an acidic pH, high osmolarity and low water content. These characteristics inhibit the growth of microorganisms, reduce oedema and promote epithelialisation. This clinical case series describes the use of a regulatory approved Leptospermum species honey ophthalmic product, in the management of post-operative corneal oedema and bullous keratopathy. Methods: A retrospective review of 18 consecutive cases (30 eyes) with corneal oedema persisting beyond one month after single or multiple ocular surgical procedures (phacoemulsification cataract surgery and additional procedures) treated with Optimel Antibacterial Manuka Eye Drops twice to three times daily as an adjunctive therapy to conventional topical management with corticosteroid, aqueous suppressants, hypertonic sodium chloride five per cent, eyelid hygiene and artificial tears. Visual acuity and central corneal thickness were measured before and at the conclusion of Optimel treatment. Results: A temporary reduction in corneal epithelial oedema lasting up to several hours was observed after the initial Optimel instillation and was associated with a reduction in central corneal thickness, resolution of epithelial microcysts, collapse of epithelial bullae, improved corneal clarity, improved visualisation of the intraocular structures and improved visual acuity. Additionally, with chronic use, reduction in punctate epitheliopathy, reduction in central corneal thickness and improvement in visual acuity were achieved. Temporary stinging after Optimel instillation was experienced. No adverse infectious or inflammatory events occurred during treatment with Optimel. Conclusions: Optimel was a safe and effective adjunctive therapeutic strategy in the management of persistent post-operative corneal oedema and warrants further investigation in clinical trials.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Standardised antibacterial Manuka honey in the management of persistent post‐operative corneal oedema: a case series

Albietz

Lenton

2015

Clinical and Experimental Optometry

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Nonclearing Corneal Edema After Phacoemulsification and Intraocular Lens Implantation

2021

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with a history of blurred vision in the right eye after phacoemulsification cataract extraction 8 weeks earlier. Current ophthalmic medications included topical prednisolone acetate, 1%, in the right eye 6 times per day. The patient reported no improvement with the treatment. On examination, his best-corrected visual acuity was 20/80 OD and 20/20 OS. Pupils were reactive without relative afferent pupillary defect, and intraocular pressures were 18 mm Hg in the right eye and 11 mm Hg in the left eye. A slitlamp biomicroscopic examination of the right eye revealed grade 2 to 3 diffuse central corneal edema and folds (Figure 1). The anterior chamber was deep and the posterior chamber intraocular lens was in good position within the capsular bag. Although the view to the posterior pole of the right eye was hazy owing to corneal edema, dilated fundus examination findings were unremarkable. Examination of the left eye revealed a few guttate. The central corneal thickness by ultrasound pachymetry was 957 μm in the right eye and 547 μm in the left eye.

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ACXL Beyond Keratoconus: Post-LASIK Ectasia, Post-RK Ectasia and Pellucid Marginal Degeneration

Mazzotta

Raiskup

Baiocchi

et al. 2017

Management of Early Progressive Corneal Ectasia

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Corneal edema after cataract surgery: Incidence and etiology

Cited by 49 publications

References 24 publications

Standardised antibacterial Manuka honey in the management of persistent post‐operative corneal oedema: a case series

Standardised antibacterial Manuka honey in the management of persistent post‐operative corneal oedema: a case series

Nonclearing Corneal Edema After Phacoemulsification and Intraocular Lens Implantation

ACXL Beyond Keratoconus: Post-LASIK Ectasia, Post-RK Ectasia and Pellucid Marginal Degeneration

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