Corneal Edema Related to Accidental Hibiclens Exposure

Reducing the risk of surgical site infections: Does chlorhexidine gluconate provide a risk reduction benefit?

“…28 However, care should be taken when applying CHG to avoid contact with the middle ear or areas adjacent to the eyes. [58][59][60] At Froedtert Hospital, patients who shower or cleanse with CHG prior to admission are instructed to avoid getting CHG in the eyes or external ear canal and to immediately rinse if they experience any burning or itching sensation following application. Is CHG bathing or cleansing an appropriate risk reduction strategy for young children or infants?…”

A Comparison of Topical Chlorhexidine, Ciprofloxacin, and Fortified Tobramycin/Cefazolin in Rabbit Models ofStaphylococcusandPseudomonasKeratitis

“…3,25 Severe ocular toxicity has been reported following the inadvertent intraocular injection and topical use with a 4% solution. 26,27 A single case report of a possible severe idiosyncratic reaction following topical 0.02% use exists in the literature. 28 In this case report, the authors also presented the possibility of anesthetic keratitis as a cause.…”

Progressive Ulcerative Keratitis Related to the Use of Topical Chlorhexidine Gluconate (0.02%)

“…Phinney et al reported accidental ocular exposure to Hibiclens in six eyes in five patients. 2 Corneal epithelial defects were noted in three patients and punctate epithelial staining was noted in the remaining two patients. The corneal epithelial defects healed in all patients within 1 week.…”