Corneal epithelial inclusion cyst in a Llama

Abstract

A 13-year-old, female Llama presented for evaluation of a limbal based corneal mass involving the OD of 4 months duration. The mass was excised en bloc by a nonpenetrating keratectomy, followed by placement of a conjunctival advancement flap covering the keratectomy site. The mass was submitted for histological evaluation. Histopathology identified the mass to be a corneal epithelial inclusion cyst filled with necrotic squamous and neutrophilic debris. Surgical excision was complete and considered curative with no signs of recurrence 3 months postoperatively. There was no known prior ocular trauma; however, a previously performed corneal biopsy for evaluation of recurrent epithelial erosions may have been an initiating cause.

Clinical and diagnostic evaluation of intraocular expulsion of a corneal epithelial inclusion cyst in a dog

“…Following displacement, the epithelium will proliferate and continuously deposit desquamated cells into the center of the cyst . These eye lesions have been previously reported in dogs, humans, llama, red deer, and a cat . The inciting cause can be trauma, previous corneal surgery, or these cysts can be congenital lesions .…”

“…Affected eyes are typically comfortable with minimal associated keratitis, but vision can be impaired by the size and location of the cyst . Surgical excision via keratectomy has been previously reported to successfully treat these corneal lesions with some cases requiring various additional grafting procedures including equine amniotic membrane, conjunctiva, and third eyelid flap . Diagnosis is confirmed using light microscopy to identify a nonkeratinized stratified squamous epithelium lining of a fluid‐filled structure .…”

“…Surgical excision via keratectomy has been previously reported to successfully treat these corneal lesions with some cases requiring various additional grafting procedures including equine amniotic membrane, conjunctiva, and third eyelid flap . Diagnosis is confirmed using light microscopy to identify a nonkeratinized stratified squamous epithelium lining of a fluid‐filled structure . This case reports describes the clinical and histopathologic findings of a corneal epithelial inclusion cyst that ruptured intraocularly.…”

Disorders of the Neurologic System and Special Senses

“…129 In rare cases, proliferative epidermal cysts will form. 136 These may be treated by nonpenetrating local keratectomy. Corneal tumors have not yet been reported.…”

Ocular Surgery

“…Conjunctival pedicle flaps have been used successfully to seal these defects and facilitate healing of the cornea of camelid patients. 1,2 This procedure is done under general anesthesia and is greatly improved with the use of an operating microscope to ease suture placement. The edges of the defect are carefully debrided and any protruding tissue (e.g.…”