Corneal Injury Threshold to Carbon Dioxide Laser Irradiation

Fine, Ben S.; Fine, Susan B.; Feigen, Larry P.; MacKeen, Donald L.

doi:10.1016/0002-9394(68)91779-0

Cited by 49 publications

(9 citation statements)

References 12 publications

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“…In addition, the present experiments show that it is the aminoacyl-tRNA-binding activity that is increased, confirming a preliminary report of Myron et al (1972). These observations resemble those seen in liver responding to damage by laser irradiation, where a fivefold increase in the activity ofpurified elongation factor 1 was found, and support the view that laser damage resembles partial hepatectomy, at least in its effect on proteinsynthesizing capacity (Fine et al, 1968;Nicholls, 1973;. In addition to an increase in [14C]phenylalanyl-tRNA-binding activity, a significant increase in the factor-dependent binding of methionyl-tRNA'Met was found in salt-wash preparations of 40S ribosomal subunits obtained from liver regenerating for 3 days.…”

Section: Discussionsupporting

confidence: 84%

“…An increased liver protein synthesis occurs a few hours after whole-body X-irradiation or y-irradiation of normal animals, though not after X-irradiation of animals undering liver regeneration (Ord & Stocken, 1961;Gerber & Altman, 1970;Hidvegi et al, 1970;Ariyama et al, 1970). Exposure of the liver area ofanimals to laser irradiation produces a form of partial hepatectomy (Fine et al, 1968) and causes an increased binding of aminoacyl-tRNA to ribosomes, i.e. elongation-factor-I activity (Nicholls, 1973;.…”

mentioning

confidence: 99%

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Growth of liver accompanied by an increased binding of aminoacyl-transfer ribonucleic acids

Nicholls¹,

Carey²,

Sendecki³

1977

Biochemical Journal

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Homogenates of rat liver obtained 3 or 14 days after partial hepatectomy were used to prepare the postmicrosomal pH 5-supernatant fraction and to prepare saltwash fractions of the 40S ribosomal subunits and the 80S ribosomes. The factordependent binding of methionyl-tRNAfMet to ribosomes and the elongation-factor-ldependent binding of phenylalanyl-tRNA to ribosomes were both increased after 3 days of growth, but not after 14 days of growth. An activity inhibitory to phenylalanyl-tRNA binding that was located in ribosomal wash fractions was decreased after 14 days of growth. Since the decreased inhibitory activity was obtained from the ribosomes and was tested against ribosomes and excess of pH5-supernatant fraction from control rat liver, its action was separate from the phenylalanyl-tRNA binding activities of the pH 5-supernatant fractions from sham-operated and regenerating liver.

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Section: Discussionsupporting

confidence: 84%

mentioning

confidence: 99%

Growth of liver accompanied by an increased binding of aminoacyl-transfer ribonucleic acids

Nicholls¹,

Carey²,

Sendecki³

1977

Biochemical Journal

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“…The victims of laser injuries typically report decreased visual acuity and visual field defects [19]. Corneal structures can be disrupted, reaching form photokeratitis until perforation [8,29,30]. The extent of intraocular damage however, is dependent on pupil size [31].…”

Section: Laser-induced Eye Injuries -Morphologic Findings and Therapymentioning

confidence: 99%

Laser and Its Hazard Potential

Hohberger¹

2016

J Nucl Med Radiat Ther

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Laser-induced eye injuries have been reported more and more often in the past years, yet the laser is not a modern invention. Based on stimulated emission, the wavelength, energy dose and pulse duration of the laser are the determining factors for its possible hazard potential. The eye, which is the most vulnerable body part for laser radiation, can be affected. As medical treatment is discussed controversial, a great demand has been put on developing laser protection gear. The present review summarizes the physical basics, clinical findings and therapeutic options of laser-induced eye injuries.

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“…Their increased activity can already be observed one day after the injury and increased cell divisions may be found a few days later [Hanke, 1915;M aumenee and Kornblueth, 1948;W eimar, 1957,1958W olter, 1958;D unnington and Smelser, 1958;Z ats and D ougelni, 1962;K itano and G oldman, 1966;F ine et al, 1968;O kamoto, 1969;P raus and D ohlman, 1969; V arga and F e h é r , 1970b].…”

Section: Cell Activity In the Corneal Regenerationmentioning

confidence: 99%