Corneal refractive surgery with femtosecond lasers

Juhász, Tibor; Loesel, Frieder H.; Kurtz, Ron M.; Horvath, Christopher; Bille, Josef F.; Mourou, G.

doi:10.1109/2944.796309

Cited by 338 publications

(190 citation statements)

References 22 publications

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“…[1][2][3] This procedure involves cutting of a thin flap in the cornea either with a fine blade (microkeratome) or a femtosecond laser (so called bladeless method) in order to expose the stromal bed for the excimer laser ablation in a laser in situ keratomileusis (LASIK) procedure, which is the most common refractive surgical method in the United States (US) today. [4][5][6][7][8] Due to the advantage of the enhanced precision and minimized collateral tissue effects, femtosecond lasers have displaced the mechanical microkeratome as the dominant tool for LASIK flap creation in the US over the past decade.…”

Section: Introductionmentioning

confidence: 99%

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

et al. 2011

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Abstract.We have developed a two-dimensional computer model to predict the temperature increase of the retina during femtosecond corneal laser flap cutting. Simulating a typical clinical setting for 150-kHz iFS advanced femtosecond laser (0.8-to 1-μJ laser pulse energy and 15-s procedure time at a laser wavelength of 1053 nm), the temperature increase is 0.2• C. Calculated temperature profiles show good agreement with data obtained from ex vivo experiments using human cadaver retina. Simulation results obtained for different commercial femtosecond lasers indicate that during the laser in situ keratomileusis procedure the temperature increase of the retina is insufficient to induce damage. C 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).

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Section: Introductionmentioning

confidence: 99%

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

et al. 2011

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“…Picosecond or femtosecond optical breakdown enables very precise and tractionless microsurgical dissections [42][43][44]. However, it is not well-suited for the selective ablation of the ILM because the achievement of this goal would require precise focusing of the laser beam with micrometer accuracy over the whole target area.…”

Section: Discussionmentioning

confidence: 99%

Photoablation of inner limiting membrane and inner retinal layers using the Erbium:YAG‐laser: An in vitro study

Hoerauf¹,

Brix²,

Winkler³

et al. 2005

Lasers Surg Med

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Background and Objectives: To explore the potential of Er:YAG-laser irradiation for precise and tractionless retinal tissue and inner limiting membrane ablation. Materials and Methods: We used free-running Er:YAGlaser irradiation (l ¼ 2.94 mm) transmitted either through a 10 cm long low-OH-quartz fiber or a 2 m long sapphire fiber that produced a more homogenous light distribution at the fiber tip. Retinal ablation in porcine retinal explants was performed under air or perfluorodecaline (PFD). Ablation depth was evaluated by optical coherence tomography (OCT) and from histologic sections. Results: A radiant exposure of 5.0 J/cm 2 delivered through a low-OH-quartz fiber and PFD caused a complete transsection of the neurosensory retina. Radiant exposures between 3.5 and 2.0 J/cm 2 resulted in marked variations of ablation depth and adjacent thermal damage. By contrast, laser pulses of 4.0 and 3.0 J/cm 2 transmitted through the sapphire fiber produced more homogenous defect patterns and less thermal damage. Close to the ablation threshold, with 1.0-2.0 J/cm 2 , ablation was limited to a 10-20 mm thin layer of the neural retina. Conclusions: We achieved in vitro ablation of inner retinal layers, but could not produce selective and reproducible ILM removal.

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“…Laser cavitation dynamics in liquids integrates several processes such as photodisruption, shockwaves generation, bubble growth and collapse, rebounding bubbles, sonoluminescence [1], and high-speed liquid jets formation [2]. Its use in medicine has led several studies about cavitation-tissue interactions, i.e., cell damage [3], tissue cutting [4,5], biomaterial remotion [5], and lithotripsy [6]. The LIC phenomenon starts after a dielectric breakdown, which is defined as a fast material ionization, it occurs when a substance that is a poor conductor of electricity is strongly ionized by absorption of electromagnetic energy [7].…”

Section: Introductionmentioning

confidence: 99%

Reconstruction of laser-induced cavitation bubble dynamics based on a Fresnel propagation approach

et al. 2015

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A single laser-induced cavitation bubble in transparent liquids has been studied through a variety of experimental techniques. High-speed video with varying frame rate up to 20 × 10 7 fps is the most suitable to study nonsymmetric bubbles. However, it is still expensive for most researchers and more affordable (lower) frame rates are not enough to completely reproduce bubble dynamics. This paper focuses on combining the spatial transmittance modulation (STM) technique, a single shot cavitation bubble and a very simple and inexpensive experimental technique, based on Fresnel approximation propagation theory, to reproduce a laser-induced cavitation spatial dynamics. Our results show that the proposed methodology reproduces a laser-induced cavitation event much more accurately than 75,000 fps video recording. In conclusion, we propose a novel methodology to reproduce laser-induced cavitation events that combine the STM technique with Fresnel propagation approximation theory that properly reproduces a laser-induced cavitation event including a very precise identification of the first, second, and third collapses of the cavitation bubble.

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Corneal refractive surgery with femtosecond lasers

Cited by 338 publications

References 22 publications

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

Photoablation of inner limiting membrane and inner retinal layers using the Erbium:YAG‐laser: An in vitro study

Reconstruction of laser-induced cavitation bubble dynamics based on a Fresnel propagation approach

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