Corneal ulcers in a tertiary hospital in Northern Nigeria

Oladigbolu, Kehinde; Rafindadi, Abdulkadir L; Abah, ER; Samaila, Elsie

doi:10.4103/1596-3519.117626

Cited by 23 publications

(24 citation statements)

References 20 publications

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“…This finding is in keeping with the study by Oladigbolu[16] in NorthernTable 2. Microbiological diagnosis.…”

supporting

confidence: 93%

“…Self-medication, patronizing quacks, use of traditional medication all contribute to the delayed presentation with patients reporting to the hospital only after failure of other modalities have been established Oladigbolu et al [16]. All the patients presented blind in the affected eye with visual acuity ranging from light perception to counting fingers at 1 metre.…”

Section: Discussionmentioning

confidence: 99%

“…In Nigeria several predisposing factors have been reported, the commonest being trauma and traditional eye medication [10] [11] [12] [13]. The causative organisms of corneal ulcer differ significantly across regions and have been found to be influenced by climate and socio-economic factors [9] [13] [14] [15] [16]. In developed countries, viruses are the predominant aetiologic agents [19].…”

Section: Introductionmentioning

confidence: 99%

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A Preliminary Report of Predisposing Factors and Predominant Microbiological Diagnosis of Corneal Ulcers Seen at the Federal Teaching Hospital Abakaliki, Nigeria

Ogbonnaya¹,

Walter-Ugwuocha²,

Ezeanosike³

et al. 2019

OJOph

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Background: Microbial keratitis often results in poor visual outcome despite treatment. A revision of treatment protocol based on local evidence may be required in order to obtain better treatment outcome. Objectives: To determine the predisposing factors and predominant microbiological diagnosis of corneal ulcers seen at the Federal Teaching Hospital Abakaliki (FETHA), Ebonyi State, Nigeria. Materials and Methods: This is a preliminary report of an on-going longitudinal descriptive study of all consenting corneal ulcer patients managed at the FETHA eye clinic over a 4-month period. Information obtained were socio-demographic data, presenting complaints, duration of symptoms prior to presentation, history of preceding trauma, medications used before presentation, presenting and final visual acuity and microbiological diagnosis. Results: A diagnosis of corneal ulcer was made in 8 out of the 852 outpatients seen over the study period giving a hospital prevalence rate of 0.59%. Five patients (62.50%) were males, five (62.50%) were farmers and 4 patients (50%) were above 60 years of age. The microbial diagnoses were bacterial keratitis 37.5% (Staphylococcus aureus), fungal keratitis 25% (Fusarium spp. and aspergillus) and acanthamoeba (25%)

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“…This finding is in keeping with the study by Oladigbolu[16] in NorthernTable 2. Microbiological diagnosis.…”

supporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Preliminary Report of Predisposing Factors and Predominant Microbiological Diagnosis of Corneal Ulcers Seen at the Federal Teaching Hospital Abakaliki, Nigeria

Ogbonnaya¹,

Walter-Ugwuocha²,

Ezeanosike³

et al. 2019

OJOph

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“…1 Post-traumatic abrasions are a common problem in humans in both developed 2 and Third World countries. 3,4 According to the World Health Organization, it is estimated that corneal opacities, including corneal ulceration, are the fourth leading cause of blindness worldwide. 5 The same is true in canine and feline patients where many corneal ulcerations have a traumatic origin and can lead to corneal blindness.…”

mentioning

confidence: 99%

Topical Cross-Linked HA-Based Hydrogel Accelerates Closure of Corneal Epithelial Defects and Repair of Stromal Ulceration in Companion Animals

Williams

Wirostko²,

Gum

et al. 2017

Invest. Ophthalmol. Vis. Sci.

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“…[14] A study in Northern Nigeria reported that 0.4% of patients with corneal ulcers were associated with use of contact lenses. [15]…”

Section: Discussionmentioning

confidence: 99%

Clinical pattern and antibiotic sensitivity of bacterial corneal ulcers in Kano, Northern Nigeria

Abubakar¹,

Abdu

Muhammad

2018

Ann Afr Med

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Purpose:The purpose of this study is to determine predisposing factors, common bacterial causes, and antibiotic sensitivity of corneal ulcers in Murtala Muhammad Specialist Hospital.Materials and Methods:A prospective, cross-sectional, observational study was carried out on patients with corneal ulcers. Information on relevant clinical, sociodemographic profile was obtained. Examination includes visual acuity test and slit-lamp biomicroscopy, especially fluorescein staining. Corneal scrapings from the ulcer were inoculated onto the selected solid culture media plates. Gram staining for microscopic examination was done. Antibiotic sensitivity test on different antibiograms was done using modified Kirby–Bauer technique, determining bacterial isolate sensitivity or resistance to relevant antibiotics (chloramphenicol, ciprofloxacin, ofloxacin, gentamicin, tetracycline, ceftazidime, ceftriaxone, cefotaxime, and penicillin).Results:A total of 77 patients with corneal ulcer were examined. Ocular trauma, application of harmful traditional eye medication, and use of unspecified topical medication before presentation were among the predisposing factors. Bacterial growth was seen in 46.8% of the samples, of which 28.6% of the growth were Gram-positive. The common bacteria isolated were Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, Proteus species, and Klebsiella pneumoniae. Isolates were sensitive to ciprofloxacin and ofloxacin while an intermediate sensitivity was seen with chloramphenicol and gentamicin. Isolates were resistant to tetracycline, ceftazidime, ceftriaxone, cefotaxime, and penicillin.Conclusion:Ocular trauma was the major predisposing factor to corneal ulcer, and Staphylococcus species was the major bacterial organism isolated. Isolates were found to be sensitive to ciprofloxacin and ofloxacin, while an intermediate sensitivity was seen with chloramphenicol and gentamicin.

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Corneal ulcers in a tertiary hospital in Northern Nigeria

Abstract: In this study most patients with corneal ulcer presented with poor vision and excessive lacrimation. Trauma was the commonest predisposing factor with bacterial organisms as the commonest isolate.

Cited by 23 publications

References 20 publications

A Preliminary Report of Predisposing Factors and Predominant Microbiological Diagnosis of Corneal Ulcers Seen at the Federal Teaching Hospital Abakaliki, Nigeria

A Preliminary Report of Predisposing Factors and Predominant Microbiological Diagnosis of Corneal Ulcers Seen at the Federal Teaching Hospital Abakaliki, Nigeria

Topical Cross-Linked HA-Based Hydrogel Accelerates Closure of Corneal Epithelial Defects and Repair of Stromal Ulceration in Companion Animals

Clinical pattern and antibiotic sensitivity of bacterial corneal ulcers in Kano, Northern Nigeria

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