This paper deals with the negative effects of the in-vehicle network on the integrated anti-slip control (ASC) and direct yaw-moment control (DYC) of all-wheel-independent-drive electric vehicles (AWID-EVs). In the integrated control design of the modern AWID-EVs, increasing control components, e.g., sensors, controllers, and actuators, are usually connected via an in-vehicle network, such as a controller area network (CAN), rather than the traditional point-to-point communication. However, the application of CAN would also bring about unexpected problems, e.g., signal asynchrony, multiple-package transmission, and signal delay, which may degrade the control performance and even destroy the stability of the system. This paper presents a co-design methodology to deal with all these challenges caused by CAN and guarantees a satisfactory vehicle dynamics performance. First, a hierarchical structure is designed for the integrated ASC and DYC control of AWID-EVs over CAN, and an active torque distribution strategy based on a well-known maximum transmissible torque estimation approach is adopted. Then, a scheduling-based communication idea is introduced to deal with all these problems caused by CAN. Third, a Lyapunov-based pole assignment theory is applied to estimate the parameter values in the scheduling design and to guarantee the satisfactory dynamic performance of the control system. A generalized linear quadratic regulator controller is designed for the system synthesis to ensure the tracking control of the vehicle. Finally, simulations and preliminary hardware-in-loop tests indicate that the proposed co-design methodology can deal with the negative effects of the in-vehicle network and ensure reliable vehicle dynamics performance.INDEX TERMS All-wheel-independent-drive electric vehicle (AWID-EV), anti-slip control (ASC), direct yaw-moment control (DYC), co-design of scheduling and control, controller area network (CAN).