Coronary anomaly in Behçet's syndrome

Siepmann, Martin; Kirch, W.

doi:10.1007/pl00006848

Cited by 17 publications

(8 citation statements)

References 15 publications

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“…Vascular involvement in BD has unique properties among other vasculitides so that it can involve arteries, veins, and vessels of all sizes. However, coronary involvement in BD is extremely rare and reported anecdotally in the English literature (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14). In our series of 137 patients with BD, 38 had vascular manifestations, but none of those patients had coronary involvement (15).…”

Section: Discussionmentioning

confidence: 99%

Myocardial Infarction and Deep Venous Thrombosis in a Young Patient with Behçet Disease

Çalgünerı

Aydemir

Öztürk

et al. 2006

Clin Appl Thromb Hemost

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Behçet disease (BD) is a chronic relapsing systemic vasculitic disorder affecting the arteries, veins, and vessels of any size. Vascular lesions in BD usually represent an occlusive nature suggesting a hypercoagulable/ prothrombotic state. Coronary arteries are rarely involved in BD. In this report, a 27-year-old male patient in whom myocardial infarction developed secondary to coronary arterial thrombosis together with deep venous thrombosis was presented. This is a review of the pathologic hemostasis and the prothrombotic state of BD.

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Section: Discussionmentioning

confidence: 99%

Myocardial Infarction and Deep Venous Thrombosis in a Young Patient with Behçet Disease

Çalgünerı

Aydemir

Öztürk

et al. 2006

Clin Appl Thromb Hemost

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“…Coronary angiography in another patient showed complete proximal occlusion of the circumflex artery and an aneurysmal fistula between the left main branch and the pulmonary artery. 176 Rarely, myocardial infarction has been the presenting symptom of BD. 173 Myocardial infarction with normal coronary arteries in young patients has been observed, presumed to be due to coronary arteritis.…”

Section: Endocardiummentioning

confidence: 99%

Behçet’s disease: an update on pathogenesis, diagnosis and management of vascular involvement

Kaklamanis

Calamia

2010

Rheumatol Rep

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The objective of this review is to summarize reports of the prevalence, clinical presentation, diagnostic methodology and treatment of vasculitic manifestations of Behçet’s disease (BD). We performed a literature search on vasculitis in BD. Articles were selected which provided insight into the pathogenesis and clinical aspects of vasculitis. Vasculitis underlies many of the clinical features of BD. Small vessel vasculitis is often found in the pathology of the mucocutaneous manifestations of BD. Large vessel vasculitis has been reported in 15-40% of BD patients. Ultrasound, angiography and tomography are applied to confirm the diagnosis when venous involvement is suspected. Endothelial dysfunction plays a role in the pathogenesis of disease. Peripheral arterial involvement in BD occurs in the form of arterial occlusion or aneurysms. Pulmonary arterial involvement is often life-threatening. The cause of cardiac vascular involvement requires an aggressive diagnostic approach. Corticosteroids and immunosuppressive agents have been used successfully in the early stage of large vessel disease and should be used as an adjunct to surgery. An increasing amount of data is available regarding the role of anti-tumor necrosis factor (TNF) agents for the treatment of BD. Anticoagulant therapy may be hazardous in patients with aneurysmal dilatation of the pulmonary vascular tree and is not effective in the treatment of venous thrombosis. Inflammation of small and large vessels is very frequent in BD. Both arteries and veins may be involved. Early recognition and appropriate management of large vessel vasculitis in BD is essential to reduce associated morbidity and mortality

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“…Bei Befall des Nervensystems mit neurologischer Symptomatik wird von einem Neuro-Behçet-Syndrom bzw. bei Gefäßbefall von Angio-oder Vaskulo-Behçet-Syndrom gesprochen [13,15,16]. Pathologisch-anatomisch liegen den Schleimhautveränderungen überwiegend lymphomonozytäre Infiltrationen zugrunde.…”

Section: As Behçet-syndrom Ist Eine Inunclassified