2001
DOI: 10.1148/radiology.219.1.r01ap37270
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Coronary Arteries: Magnetization-prepared Contrast-enhanced Three-dimensional Volume-targeted Breath-hold MR Angiography

Abstract: A volume-targeted contrast agent-enhanced breath-hold coronary magnetic resonance angiographic technique was optimized and evaluated in 16 volunteers. Substantial increases in coronary signal-to-noise ratio, contrast-to-noise ratio, lengths of depiction, and vessel sharpness were observed on enhanced images. The imaging approach with two 20-mL injections of contrast agent covers the left and right coronary arteries in two breath holds and is a promising method for coronary imaging.

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Cited by 111 publications
(96 citation statements)
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“…For the evaluation of the vessel sharpness, we used a measure introduced in (Li et al 2001) and extended it to a semi-automatic evaluation of whole vessel branches ( Figure 4 illustrates the process):…”
Section: Vessel Sharpnessmentioning
confidence: 99%
See 1 more Smart Citation
“…For the evaluation of the vessel sharpness, we used a measure introduced in (Li et al 2001) and extended it to a semi-automatic evaluation of whole vessel branches ( Figure 4 illustrates the process):…”
Section: Vessel Sharpnessmentioning
confidence: 99%
“…The following algorithm is applied to each profile line l at each evaluation point (cf. Figure 4c) (Li et al 2001). It is important to note that all intensity measurements are taken from the original, non-windowed volumes.…”
Section: Vessel Sharpnessmentioning
confidence: 99%
“…van Geuns et al [7] assessed the diagnostic accuracy of this approach and reported that 69% of segments were assessable, with sensitivity and specificity of 92% and 68%, respectively, for the detection of >50% luminal stenosis. One advantage of the breath-hold technique is that it allows for imaging of coronary arteries during the first pass of extracellular MR contrast media (e.g., Gd-DTPA), which rapidly diffuses from the intravascular space to the interstitial space after intravenous administration [8][9][10][11]. Regenfus et al [11] obtained breath-hold 3D coronary MRA immediately after injecting extracellular MR contrast agent at a flow rate of 1 ml/s and reported 94% sensitivity and 57% specificity for detecting significant CAD.…”
Section: Introduction Coronary Mra; Achilles Heel Of Cardiac Mri?mentioning
confidence: 99%
“…Current 3D breath-hold acquisition schemes with breath-hold durations of 10 -40 s for a very limited number of slab partitions have been reported in several studies (15)(16)(17). In those studies, segmentation of in-plane data acquisition with up to four cardiac cycles for each slice partition was chosen to restrict the acquisition window to mid-diastole while counterbalancing breath-hold time constraints.…”
mentioning
confidence: 99%