1997
DOI: 10.1016/s1010-7940(96)01107-4
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Coronary artery bypass surgery in women and in men; early and long-term results. A study of the Norwegian population adjusted by age and sex

Abstract: The risk of early mortality and low-output syndrome needing intra-aortic balloon support tended to be higher in women compared with men. Women did not run an increased risk of total mortality, recurrent angina or of total non-fatal myocardial infarction. The standard mortality ratio was increased in both men and women, but in particular higher in women, suggesting a more aggressive course of coronary artery disease in operated women than in operated men. However, this difference did not show in the long term f… Show more

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Cited by 36 publications
(33 citation statements)
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“…Although long-term outcomes with CABG in women are similar to or even better than those in men, women have higher rates of periprocedural morbidity and mortality. [1133][1134][1135][1136][1137][1138][1139] Several hypotheses have been suggested to explain this increased morbidity and mortality, including older age at presentation, more frequent need for urgent revascularization, more comorbid conditions, smaller body surface area and coronary arterial dimensions, and increased risk of bleeding. The fact that women on average are older than men at the time of CABG is thought, at least in part, to be due to the loss of the protective effects of estrogen with menopause.…”
Section: Womenmentioning
confidence: 99%
See 1 more Smart Citation
“…Although long-term outcomes with CABG in women are similar to or even better than those in men, women have higher rates of periprocedural morbidity and mortality. [1133][1134][1135][1136][1137][1138][1139] Several hypotheses have been suggested to explain this increased morbidity and mortality, including older age at presentation, more frequent need for urgent revascularization, more comorbid conditions, smaller body surface area and coronary arterial dimensions, and increased risk of bleeding. The fact that women on average are older than men at the time of CABG is thought, at least in part, to be due to the loss of the protective effects of estrogen with menopause.…”
Section: Womenmentioning
confidence: 99%
“…1139 Some investigators have shown that smaller body surface area, a surrogate for coronary arterial size, is associated with higher risk of perioperative mortality, whereas others have not. 1140 Women use more hospital resources in the perioperative period than do men, including intra-aortic balloon counterpulsation, 1137 vasopressors, mechanical ventilation, dialysis, and blood products, 1154,1159 all of which are associated with higher mortality rates. 1146,1160,1161 Women are more likely to have wound complications and longer ICU and hospital stays.…”
Section: Womenmentioning
confidence: 99%
“…379,422,[428][429][430][431] In some studies, women had even better long-term survival than men after adjusting for risk factors. 379,420 The reasons for improved longterm, but not short-term, survival are speculative.…”
Section: Long-term Mortalitymentioning
confidence: 99%
“…In Brazil, at the analysis of more than 115,000 heart surgeries carried out between 2000 and 2003, the reported mortality was 8%. The main risk factors for death during valve replacement surgeries are: advanced age 4 , female sex [5][6][7] , chronic obstructive pulmonary disease (COPD) 8,9 , New York Heart Association functional class (NYHA-FC), ventricular dysfunction, surgical priority (urgency/emergency), pulmonary arterial hypertension (PAH) 10 , renal dysfunction 11 , valvular disease associated with ischemic cardiopathy 12 , reoperation [13][14][15][16] and infectious endocarditis [17][18][19][20] .…”
Section: Introductionmentioning
confidence: 99%