Coronary artery calcification—does it predict the CAD-RADS category?

Moradi, Maryam; Rafiei, Ebrahim; Rasti, Sina; Haghbin, Hossein

doi:10.1007/s10140-022-02082-w

Cited by 1 publication

(1 citation statement)

References 35 publications

(29 reference statements)

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“…In conclusion, the study [ 31 ] provides a simple rule of thumb (men < 50 years and women < 60 years with any CACS, men < 60 years and women < 70 years with CAC S > 100) for identifying CACS > 75th percentile that might be readily adopted in clinical practice. CACS could predict coronary artery disease reporting and data system (CAD-RADS) with an accuracy of 80% [ 32 ]. Several personalized risk prediction tools, including CACS, polygenic risk scores, and metabolic risk scores may be able to improve risk assessment [ 33 ].…”

Section: Calcium Score and Atherosclerosismentioning

confidence: 99%

Subclinical Hypertension-Mediated Organ Damage (HMOD) in Hypertension: Atherosclerotic Cardiovascular Disease (ASCVD) and Calcium Score

Rizzoni

Agabiti-Rosei

Ciuceis

et al. 2022

High Blood Press Cardiovasc Prev

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Calcium controls numerous events within the vessel wall. Permeability of the endothelium is calcium dependent, as are platelet activation and adhesion, vascular smooth muscle proliferation and migration, and synthesis of fibrous connective tissue. Double-helix computerized tomography is a noninvasive technique that can detect, measure, and compare coronary calcification in the coronary arteries. Despite some convincing evidence about the prognostic value and usefulness of coronary artery calcium score (CACS) in the stratification of cardiovascular risk in the high risk general population and also in hypertensive patients, current guidelines for the management of hypertension, do not include such evaluation among the recommended procedures to be performed in the majority of patients even with the intent to detect hypertension-mediated organ damage (HMOD) in an early phase. On the contrary, the European Society of Cardiology guidelines for the diagnosis and management of chronic coronary syndromes, the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease, and the 2018 Cholesterol Clinical Practice Guidelines indicate that the evaluation of CACS may be of some usefulness in specific subpopulations, although this view is not accepted in the US Preventive Services Task Force document. Very recently, the European Society of Cardiology Guidelines on cardiovascular disease prevention in clinical practice stated that CACS estimation may be considered to improve risk classification around treatment decision thresholds. In conclusion, the use of CACS as a diagnostic tool is still controversial. While some evidence exists about is ability to improve stratification of cardiovascular risk in primary prevention, in particular in selected patients who are at intermediate or borderline risk of atherosclerotic cardiovascular disease, there is insufficient evidence to use it as a standard means to assess HMOD.

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Section: Calcium Score and Atherosclerosismentioning

confidence: 99%