Coronary artery calcium score and coronary computed tomography angiography for patients with asymptomatic polyvascular (non-coronary) atherosclerosis

Cecere, Annagrazia; Riccioni, Graziano; Sforza, Nicola; Marano, Riccardo; Guglielmi, Giuseppe

doi:10.11622/smedj.2016186

Cited by 3 publications

(2 citation statements)

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“…Similarly, Cecere and his colleagues assessed the prevalence of CAD using CCTA among patients with aortic, carotid and femoral atherosclerosis. They observed positive correlation between polyvascular atherosclerosis and abnormal CCTA [5].…”

Section: Discussionmentioning

confidence: 91%

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Incidence of Coronary Atherosclerosis Plaques in Patients Showing Thoracic Aortic Calcifications on a Low Dose Chest CT Scan

2023

Cardiolog Res Cardiovasc Med

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Introduction: Thoracic aortic calcification (TAC) and coronary artery disease (CAD) share the same risk factors. The main objective of this study is to evaluate the incidence of CAD on coronary artery calcium scoring (CACS) and coronary computed tomography angiography (CCTA) when TAC are present on low dose chest computed tomography (LDCT).Methods: Patients underwent a LDCT with either a CACS or CCTA. Visual assessment of TAC was done for the LDCT, while imaging reports were reviewed for CACS and CCTA findings.Results: Among 504 patients, 50.2% underwent a CCTA and 49.8% a CACS. Out of the 504 patients, 280 patients (55.6%) had TAC. 71.4% of patients with TAC were males, and the mean age of patients with TAC was high (mean = 60.9 ± 10.2 years) compared to patients with no TAC (mean = 46.9 ± 8.4 years) (p < 0.001). The mean calcium score (mean = 262.6 ± 555.9 mg/Dl) and the rate of abnormal CCTA (81.3%) were higher in patients with TAC compared to non-TAC patients (36.8%) (p < 0.001). Conclusion:Our study showed that patients with TAC had a positive CACS that was higher than the one in patients without TAC. Moreover, patients with TAC had abnormal findings on CCTA.

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Section: Discussionmentioning

confidence: 91%

“…In the USA, the MESA study showed that TAC have the same traditional risk factors as CVD and that descending TAC are a strong predictor of CAD [3][4]. Similar studies were conducted in Italy, Germany, Korea, and Israel [5][6]. However, no studies evaluated simultaneously the incidence of CAD by CAC score or CCTA when TAC were present.…”

Section: Introductionmentioning

confidence: 96%

Incidence of Coronary Atherosclerosis Plaques in Patients Showing Thoracic Aortic Calcifications on a Low Dose Chest CT Scan

2023

Cardiolog Res Cardiovasc Med

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Comparison of ct angiography and scoring systems for cardiovascular risk stratification in asymptomatic patients

Rozhkov¹,

Shchekochikhin²,

Tebenkova³

et al. 2023

Kardiol. serdechno-sosud. khir.

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Patients with Polyvascular Disease: A Very High-risk Group

Manolis

2022

CVP

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Polyvascular disease (PolyvascDis) with atherosclerosis occurring in >2 vascular beds (coronary, carotid, aortic, visceral and/or peripheral arteries) is encountered in 15-30% of patients who experience greater rates of major adverse cardiovascular (CV) events. Every patient with multiple CV risk factors or presenting with CV disease in one arterial bed should be assessed for PolyvascDis clinically and noninvasively prior to invasive angiography. Peripheral arterial disease (PAD) can be readily diagnosed in routine practice by measuring the ankle-brachial index. Carotid disease can be diagnosed by duplex ultrasound showing % stenosis and/or presence of plaques. Coronary artery disease (CAD) can be screened by determining coronary artery calcium score using coronary computed tomography angiography; further non-invasive testing includes exercise stress and/or myocardial perfusion imaging or dobutamine stress test, prior to coronary angiography. Abdominal ultrasound can reveal an abdominal aortic aneurysm. Computed tomography angiography will be needed in patients with suspected mesenteric ischemia to assess the mesenteric arteries. Patients with acute coronary syndrome and concomitant other arterial disease have more extensive CAD and poorer CV outcomes. Similarly, PolyvascDis in patients with carotid disease and/or other PAD is independently associated with an increased risk for all-cause and CV mortality during long-term follow-up. Treatment of patients with PolyvascDis should include aggressive management of all modifiable risk factors by lifestyle changes and drug therapy, with particular attention to patients who are commonly undertreated, such as those with PAD. Revascularization should be reserved for symptomatic vascular beds, using the least aggressive strategy in a multidisciplinary vascular team approach.

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Coronary artery calcium score and coronary computed tomography angiography for patients with asymptomatic polyvascular (non-coronary) atherosclerosis

Cited by 3 publications

References 50 publications

Incidence of Coronary Atherosclerosis Plaques in Patients Showing Thoracic Aortic Calcifications on a Low Dose Chest CT Scan

Incidence of Coronary Atherosclerosis Plaques in Patients Showing Thoracic Aortic Calcifications on a Low Dose Chest CT Scan

Comparison of ct angiography and scoring systems for cardiovascular risk stratification in asymptomatic patients

Patients with Polyvascular Disease: A Very High-risk Group

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