2008
DOI: 10.2214/ajr.07.3112
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Coronary Artery Disease After Radiation Therapy for Hodgkin's Lymphoma: Coronary CT Angiography Findings and Calcium Scores in Nine Asymptomatic Patients

Abstract: Coronary CT angiography and calcium scores are useful tools for evaluation of irradiation-related coronary artery disease. Complementary tests might be necessary in selected patients. Prospective larger studies are needed to better define the role of coronary CT angiography and calcium scores and to establish an algorithm for evaluation and treatment of these patients.

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Cited by 92 publications
(75 citation statements)
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“…Page 2, line 10-11: A common localization of coronary lesions after radiotherapy is at the ostial or proximal segment, with a distal disease-free vasculature (8). 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 Erythrocyte sedimentation rate (ESR) and C-reactive protein were within the normal range.…”
Section: Reviewer Commentmentioning
confidence: 99%
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“…Page 2, line 10-11: A common localization of coronary lesions after radiotherapy is at the ostial or proximal segment, with a distal disease-free vasculature (8). 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 Erythrocyte sedimentation rate (ESR) and C-reactive protein were within the normal range.…”
Section: Reviewer Commentmentioning
confidence: 99%
“…A common localization of coronary lesions after radiotherapy is at the ostial or proximal segment, with a distal disease-free vasculature (8).…”
Section: Coronary Arterial Involvement Inmentioning
confidence: 99%
“…5 In a case series that included nine patients, Rademaker et al stated that CTA and calcium scoring are useful methods for the assessment of coronary artery disease (CAD) related to irradiation. 10 Compared to catheter angiography, CTA is a noninvasive method with a high negative predictive value. CTA can reveal the effect of radiation and wall thickening of soft tissues in addition to the vascular lumen.…”
mentioning
confidence: 99%
“…Besides the advantage of having lower costs in comparison to traditional invasive angiography, CTA acquires information regarding the vessel wall and enables the identification of pathologic vessels and additional extravascular abnormalities. 10,11 CTA is also able to detect calcium in the vessel lining, with high sensitivity. 10 However, invasive coronary angiography cannot be recommended based only on coronary calcium scoring, due to its low specificity.…”
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confidence: 99%
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